Results 171 to 180 of about 1,202,909 (308)

Lysicamine Reduces Protein Kinase B (AKT) Activation and Promotes Necrosis in Anaplastic Thyroid Cancer. [PDF]

Pharmaceuticals (Basel), 2023
Rodrigues MT, Michelli APP, Caso GF, de Oliveira PR, Rodrigues-Junior DM, Morale MG, Machado Júnior J, Bortoluci KR, Tamura RE, da Silva TRC, Raminelli C, Chau E, Godin B, Calil-Silveira J, Rubio IGS.   +14 more
europepmc   +1 more source

Involvement of protein kinase B and mitogen-activated protein kinases in experimental normothermic liver ischaemia–reperfusion injury [PDF]

, 2006
Raffaele Cursio, Nathalie Filippa, Claudia Miele, E Van Obberghen, Jean Gugenheim   +4 more
openalex   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Combined inhibition of protein kinase B and enhancer of zeste homolog 2: a novel strategy to induce triple-negative breast cancer cell death. [PDF]

Mol Biomed
Zhu X, Wang Y, Zhang L.
europepmc   +1 more source

Styela clava methanolic extract protects against alcohol-induced liver injury by inhibiting uclear factor-kappa B (NF-κB) and mitogen-activated protein kinases (MAPK) pathways

N.M. Liyanage, D. P. Nagahawatta, Jun-Geon Je, Young-Sang Kim, Ah-Reum Kim, In-Cheol Lee, Jae‐Il Kim   +6 more
openalex   +2 more sources

Leonurine Exerts Anti-Catabolic and Anti-Apoptotic Effects via Nuclear Factor kappa B (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways in Chondrocytes

, 2019
Pengfei Hu, Fangfang Sun, Jing Qian
openalex   +2 more sources

12-O-tetradecanoylphorbol-1, 3-acetate induces the negative regulation of protein kinase B by protein kinase Cα during gastric cancer cell apoptosis [PDF]

, 2010
Bing Zhang, Chun Xia
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Inhibition of nuclear receptor coactivator 5 overcomes acquired lenvatinib resistance driven by protein kinase B-mammalian target of rapamycin signaling in hepatocellular carcinoma. [PDF]

Anticancer Drugs
Zhou H, Zhang Q, Yang L, Pan Z, Zheng H, Zhang Z, Li D, Li G, Liu X, Bao X, Liu C, Zhang W.   +11 more
europepmc   +1 more source

Regulation of AMP-activated protein kinase by cAMP in adipocytes: Roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis

, 2009
Bilal Omar, Emilia Zmuda‐Trzebiatowska, Vincent C. Manganiello, Olga Göransson, Eva Degerman   +4 more
openalex   +2 more sources