Results 211 to 220 of about 3,162,793 (373)

Intermittent pH changes suggest acceleration of the extracellular signal-regulated kinase 1/2 (ERK1/2) mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3 kinase (PI3K)/ protein kinase B (AKT) pathways.

Ryota Nishida (22258400), Tomoaki Fukui (4777479), Kenichi Sawauchi (22258403), Yohei Kumabe (4777482), Hyuma Kondo (22258406), Yuya Yamamoto (667024), Kyohei Takase (22258409), Ryo Yoshikawa (5075996), Takahiro Niikura (344625), Ryosuke Kuroda (735024), Keisuke Oe (344623)   +10 more
openalex   +1 more source

The p75 Neurotrophin Receptor Activates Akt (Protein Kinase B) through a Phosphatidylinositol 3-Kinase-dependent Pathway [PDF]

, 2001
Philippe P. Roux, Asha Bhakar, Timothy E. Kennedy, Philip A. Barker   +3 more
openalex   +1 more source

Assaying AKT/Protein Kinase B Activity

, 2003
Kyle L, Hoehn, Scott A, Summers
openaire   +2 more sources

Emerging role of FKBP51 in AKT kinase/protein kinase B signaling [PDF]

Cell Cycle, 2010
Huadong, Pei, Zhenkun, Lou, Liewei, Wang
openaire   +2 more sources

Protein Kinase B/Akt Participates in GLUT4 Translocation by Insulin in L6 Myoblasts

Molecular and Cellular Biology, 1999
Qinghua Wang, R. Somwar, P. Bilan, Zhi Liu, Jing-Yun Jin, J. Woodgett, A. Klip   +6 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Design, Synthesis, and Evaluation of Naphthyl Pyrazino-Pyrido-Pyrimidinones Targeting the Phosphoinositide 3-Kinase/Alpha-Serine/Protein Kinase B/Mammalian Target of Rapamycin Pathway. [PDF]

ChemistryOpen
Marchiori MF, da Silva G, Kawano DF, Leopoldino AM, Madruga E, Martinez A, Carvalho I.   +6 more
europepmc   +1 more source

Leonurine Exerts Anti-Catabolic and Anti-Apoptotic Effects via Nuclear Factor kappa B (NF-κB) and Mitogen-Activated Protein Kinase (MAPK) Signaling Pathways in Chondrocytes

, 2019
Pengfei Hu, Fangfang Sun, Jing Qian
openalex   +2 more sources

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase‐1 and p70 S6 kinase

FEBS Letters, 1996
D. Alessi, F. Barry Caudwell, M. Andjelkovic, B. Hemmings, P. Cohen   +4 more
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source