Results 211 to 220 of about 1,944,084 (333)

Activation of mitogen‐activated protein kinase by the bradykinin B₂ receptor is independent of receptor phosphorylation and phosphorylation‐triggered internalization [PDF]

, 1999
Andree Blaukat, Anne Pizard, Rabary M. Rajerison, François Alhenc–Gelas, Werner Müller‐Esterl, Ivan Ðikić   +5 more
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Fast detection of protein kinase B in chrysin treated colorectal cancer cells using a novel multicore microfiber biosensor. [PDF]

Commun Eng
Tian Z, Xuan H, Yao Y, Hao S, Zhang Z, Zhang B, Zhang J, Zhang L, Sang X, Yuan J, Farrell G, Wu Q.   +11 more
europepmc   +1 more source

Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes. [PDF]

, 1995
Mary A. Valentine, Andrew J. Czernik, N A Rachie, Hisashi Hidaka, Cynthia L. Fisher, John C. Cambier, Karol Bomsztyk   +6 more
openalex   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway. [PDF]

J Tradit Chin Med, 2023
Xiaohui Y, Jian W, Li C, Yuxi Z, Jianlin H, Minghua L.   +5 more
europepmc   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Hinokitiol reduces tumor metastasis by regulating epithelial cell adhesion molecule via protein kinase-B/mammalian target of rapamycin signaling pathway. [PDF]

Am J Cancer Res
Wu PS, Weng JR, Chiu SH, Wu LH, Chen PH, Wang YX, Chiu PY, Lee CH.   +7 more
europepmc   +1 more source

αA-Crystallin Mediated Neuroprotection in the Retinal Neurons Is Independent of Protein Kinase B. [PDF]

Front Neurosci, 2022
Nath M, Fort PE.
europepmc   +1 more source

A LYSINE(Lys)-CONTAINING PEPTIDE CORRESPONDING TO A TEN AMINOACID SEQUENCE OF PROTEIN KINASE SUBDOMAIN II PARTIALLY PREVENTS THE INHIBITORY EFFECT OF BILIRUBIN (B) ON PHOSPHOLEMMAN PHOSPHORYLATION (P) BY cAMP-DEPE [PDF]

, 1996
Thor W.R Hansen, Siri B.W Mathiesen, S. Ivar Walaas   +2 more
openalex   +1 more source