Results 251 to 260 of about 3,162,793 (373)

Pmorf0222 , a Virulence Factor in Pasteurella multocida, Activates Nuclear Factor Kappa B and Mitogen-Activated Protein Kinase via Toll-Like Receptor 1/2

, 2022
Tenglin Xu, Yating Zheng, Benjin Liu, Mingxing Kou, Qian Jiang, Jiasen Liu, Hongtao Kang, Mingfa Yang, Dongchun Guo, Liandong Qu   +9 more
openalex   +1 more source

Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib.

Journal of the National Cancer Institute, 2005
D. Haas-Kogan, M. Prados, T. Tihan, D. Eberhard, N. Jelluma, Nils D. Arvold, Rachel Baumber, K. Lamborn, A. Kapadia, M. Malec, M. Berger, D. Stokoe   +11 more
semanticscholar   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Electroacupuncture improves diabetes-associated cognitive impairment in rats: potential involvement of hippocampal insulin receptor substrates 1/phosphatidylinositol 3-kinase/protein kinase B signaling pathway activation. [PDF]

Neuroreport
Zhang L, Song H, Ye M, Kan W, Hu Y, Xie H, Yuan A.   +6 more
europepmc   +1 more source

Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Cα in chondrocytes

, 2012
Qingzhi Chen, Bing Zhang, Tingting Yi, Chun Xia   +3 more
openalex   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Decreased Phosphorylated Protein Kinase B (Akt) in Individuals with Autism Associated with High Epidermal Growth Factor Receptor (EGFR) and Low Gamma-Aminobutyric Acid (GABA)

Biomarker Insights, 2015
Anthony J. Russo
doaj  

Development of a Peptidase-Resistant Substrate for Single-Cell Measurement of Protein Kinase B Activation

, 2020
Angela Proctor, Qunzhao Wang, David S. Lawrence, Nancy L. Allbritton   +3 more
openalex   +2 more sources

Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase [PDF]

, 2007
Syed Z. Imam, Fred E. Indig, Wen‐Hsing Cheng, Satya Saxena, Tinna Stevnsner, Donald Küfe, Vilhelm A. Bohr   +6 more
openalex   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source