Results 261 to 270 of about 1,202,909 (308)

Regulation of Protein Kinase B

Journal of Receptors and Signal Transduction, 1999
Protein kinase B (PKB) is a member of the second-messenger regulated subfamily of protein kinases implicated in signalling downstream of growth factor and insulin receptor tyrosine kinases and phosphatidylinositol 3-kinase (PI 3-kinase). PKB is activated by phosphorylation in response to mitogens and survival factors.
R, Meier, B A, Hemmings
openaire   +2 more sources

Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B

Science, 1998
Protein kinase B (PKB) is activated in response to phosphoinositide 3-kinases and their lipid products phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P 3 ] and PtdIns(3,4)P 2 in the signaling pathways used by a wide variety of growth factors, antigens, and inflammatory stimuli. PKB is
L, Stephens   +11 more
openaire   +2 more sources

Regulating Protein Kinase B

Science Signaling, 2001
Protein kinase B (PKB) has proven to be a key regulatory element in growth factor signaling, cell survival, and transformation to a cancerous phenotype. Maira et al. screened for proteins that physically interacted with PKB and identified a human protein, which they call carboxyl-terminal modulator protein (CTMP ...
  +4 more sources

Protein kinases, from B to C

Biochemical Society Transactions, 2007
The PKB (protein kinase B) and PKC (protein kinase C) families display highly related catalytic domains that require a largely conserved series of phosphorylations for the expression of their optimum activities. However, in cells, the dynamics of these modifications are quite distinct.
Cameron, A. J.   +12 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy