Results 331 to 340 of about 3,162,793 (373)

The Oldest of Old Male C57B/6J Mice Are Protected from Sarcopenic Obesity: The Possible Role of Skeletal Muscle Protein Kinase B Expression. [PDF]

Int J Mol Sci
Reynolds TH, Mills N, Hoyte D, Ehnstrom K, Arata A.   +4 more
europepmc   +1 more source

Leptin protects chondrocytes by inhibiting autophagy via phosphoinositide 3 kinase/protein kinase B/mammalian target of rapamycin signaling pathway. [PDF]

Heliyon
Li P, Jiang W, Yang Q, Lu Y, Zhang J.
europepmc   +1 more source

Oxyresveratrol Enhances the Anti-Cancer Effect of Cisplatin against Epithelial Ovarian Cancer Cells through Suppressing the Activation of Protein Kinase B (AKT). [PDF]

Biomolecules
Thaklaewphan P, Wikan N, Potikanond S, Nimlamool W.   +3 more
europepmc   +1 more source

CD19 Deficiency Leads to Dysregulation of Phosphoinositide 3-Kinase-Protein Kinase B (<i>PI3K/AKT</i>) and Nuclear Factor Kappa B (<i>NF-κB</i>) Pathways: Implications for B-Cell Maturation and Immune Function. [PDF]

J Clin Pract Res
Küççüktürk S, Karaselek MA, Duran T, Reisli İ.   +3 more
europepmc   +1 more source

Intermedin Alleviates Diabetic Cardiomyopathy by Up-Regulating CPT-1β through Activation of the Phosphatidyl Inositol 3 Kinase/Protein Kinase B Signaling Pathway. [PDF]

Pharmaceuticals (Basel)
Zhao J, Han L, Zhang YR, Liu SM, Ji DR, Wang R, Yu YR, Jia MZ, Chai SB, Tang HF, Huang W, Qi YF.   +11 more
europepmc   +1 more source

Protein kinase B from Giardia intestinalis

, 2002
openaire   +2 more sources

mTORC1 and mTORC2 Co-Protect against Cadmium-Induced Renal Tubular Epithelial Cell Apoptosis and Acute Kidney Injury by Regulating Protein Kinase B. [PDF]

J Agric Food Chem
Zhu J, Gong Z, Wang X, Zhang K, Ma Y, Zou H, Song R, Zhao H, Liu Z, Dong W.   +9 more
europepmc   +1 more source

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Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B

Science, 1998
Protein kinase B (PKB) is activated in response to phosphoinositide 3-kinases and their lipid products phosphatidylinositol 3,4,5-trisphosphate [PtdIns(3,4,5)P 3 ] and PtdIns(3,4)P 2 in the signaling pathways used by a wide variety of growth factors, antigens, and inflammatory stimuli. PKB is
L, Stephens, K, Anderson, D, Stokoe, H, Erdjument-Bromage, G F, Painter, A B, Holmes, P R, Gaffney, C B, Reese, F, McCormick, P, Tempst, J, Coadwell, P T, Hawkins   +11 more
openaire   +3 more sources

Role of Akt/protein kinase B in metabolism

Trends in Endocrinology & Metabolism, 2002
Since its discovery more than a decade ago, the Ser/Thr kinase Akt/PKB (protein kinase B) has been recognized as being remarkably well conserved across a broad range of species and involved in a diverse array of cellular processes. Among its many roles, Akt appears to be common to signaling pathways that mediate the metabolic effects of insulin in ...
Eileen L, Whiteman, Han, Cho, Morris J, Birnbaum   +2 more
openaire   +3 more sources

Regulation of Protein Kinase B

Journal of Receptors and Signal Transduction, 1999
Protein kinase B (PKB) is a member of the second-messenger regulated subfamily of protein kinases implicated in signalling downstream of growth factor and insulin receptor tyrosine kinases and phosphatidylinositol 3-kinase (PI 3-kinase). PKB is activated by phosphorylation in response to mitogens and survival factors.
R, Meier, B A, Hemmings
openaire   +2 more sources