Results 141 to 150 of about 1,243,636 (309)

Protein kinase C regulation of neuronal zinc signaling mediates survival during preconditioning

, 2009
Mandar A. Aras, Hirokazu Hara, Karen A. Hartnett, Karl Kandler, Elias Aizenman   +4 more
openalex   +1 more source

Submaximal Inhibition of Protein Kinase C Restores ADP-induced Dense Granule Secretion in Platelets in the Presence of Ca2+ [PDF]

, 2011
Amanda J. Unsworth, Holly Smith, Paul Gissen, Steve P. Watson, Catherine J. Pears   +4 more
openalex   +1 more source

Identification of Myeloid Protein Kinase C Epsilon as a Novel Atheroprotective Gene. [PDF]

Arterioscler Thromb Vasc Biol
Wells AT, Bossardi Ramos R, Shen MM, Binrouf RH, Swinegar AE, Lennartz MR.   +5 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Protein Kinase C promotes peroxisome biogenesis and peroxisome-endoplasmic reticulum interaction. [PDF]

J Cell Biol
Borisyuk A, Howman C, Pattabiraman S, Kaganovich D, Amen T.   +4 more
europepmc   +1 more source

Protein Kinase C [PDF]

British Journal of Cancer, 1993
openaire   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Membrane-bound Protein Kinase C Modulates Receptor Affinity and Chemotaetic Responsiveness of Lewis Lung Carcinoma Sublines to an Elastin-derived Peptide

, 1989
C H Blood, Bruce R. Zetter
openalex   +1 more source

C-spine mutations of protein kinase C and Akt as a novel generalizable approach to create stable pseudokinases. [PDF]

J Biol Chem
Hodapp SJ, Kao TH, Wu J, Balasuriya N, Antal CE, Taylor SS, Newton AC.   +6 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source