Results 181 to 190 of about 843,778 (210)

Physiological functions of protein kinase inhibitors

2000
Protein kinases are key regulatory enzymes involved in a multitude of biochemical pathways. This chapter will describe the current research on targeting specific protein kinases with inhibitors in attempts to disrupt flux through specific pathways.
M. Ho, John J. Turchi
openaire   +3 more sources

Discovery of Protein Kinase Phosphatase Inhibitors

2006
Dynamic protein phosphorylation, a major cellular regulatory system, is tightly controlled by coordinating the reversible action of protein kinases and phosphatases. Recent evidence is consistent with sophisticated mechanisms that regulate both kinases and phosphatases in the cell.
John S. Lazo, Andreas Vogt
openaire   +3 more sources

Inhibitors of protein kinases

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013
Doriano Fabbro, David Shugar
openaire   +2 more sources

Inhibitors of protein kinase C

Cellular Signalling, 1994
W. J. Ryves, Gordge Pc
openaire   +3 more sources

Trends in kinase drug discovery: targets, indications and inhibitor design

Nature Reviews Drug Discovery, 2021
Helgi B Schiöth, Misty M Attwood, Stefan Knapp   +2 more
exaly  

Kinase drug discovery 20 years after imatinib: progress and future directions

Nature Reviews Drug Discovery, 2021
Darren Cross, Pasi A Jänne, Philip Cohen   +2 more
exaly  

Kinase inhibition in autoimmunity and inflammation

Nature Reviews Drug Discovery, 2021
Ali A Zarrin, Bruno Hochhegger, Katherine Bao   +2 more
exaly  

Protein kinase C inhibitors

Drugs of the Future, 1993
E. J. Lewis, Sandra E. Wilkinson, W. Harris, Hill Christopher Huw, J.S. Nixon   +4 more
openaire   +2 more sources

Protein Kinase Inhibitors

2002
openaire   +1 more source

Lung cancer: New biological insights and recent therapeutic advances

Ca-A Cancer Journal for Clinicians, 2011
Suresh S Ramalingam, Taofeek K Owonikoko, Fadlo R Khuri   +2 more
exaly