Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells. [PDF]
T G Lee+3 more
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Osmotic pressure‐induced calcium response states
Acute hypotonic stress triggers distinct calcium response patterns in HEK293T cells. These signals originate from the endoplasmic reticulum via RyR2 and propagate to neighboring cells through gap junctions. This result highlights a novel calcium‐dependent mechanism underlying the intracellular and intercellular response to osmotic pressure.
Zidan Gao+2 more
wiley +1 more source
Editorial: Protein kinase inhibitors in neurodegeneration and cancer targeted therapies. [PDF]
Anwar S, Ahmed A, Sarli V, Hassan I.
europepmc +1 more source
Selective inhibition of human neutrophil functional responsiveness by erbstatin, an inhibitor of tyrosine protein kinase [PDF]
PH Naccache+7 more
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Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto+5 more
wiley +1 more source
[Retracted] Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: A rationale to combine targeted drugs based on protein expression inhibition profiles. [PDF]
Aftimos PG+5 more
europepmc +1 more source
Aromatic Rings as Molecular Determinants for the Molecular Recognition of Protein Kinase Inhibitors. [PDF]
Zhu Y, Alqahtani S, Hu X.
europepmc +1 more source
The 5‐HT4 receptor subtype inhibits K+ current in colliculi neurones via activation of a cyclic AMP‐dependent protein kinase [PDF]
Laurent Fagni+3 more
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Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi+5 more
wiley +1 more source