Results 261 to 270 of about 2,078,021 (401)

Molecular Mechanisms of Alzheimer's Disease Induced by Amyloid-β and Tau Phosphorylation Along with RhoA Activity: Perspective of RhoA/Rho-Associated Protein Kinase Inhibitors for Neuronal Therapy. [PDF]

Cells
Ahn EH, Park JB.
europepmc   +1 more source

Current progress, challenges and future prospects of indazoles as protein kinase inhibitors for the treatment of cancer. [PDF]

RSC Adv, 2021
Tandon N, Luxami V, Kant D, Tandon R, Paul K.   +4 more
europepmc   +1 more source

An antisense oligodeoxynucleotide targeted against the type II beta regulatory subunit mRNA of protein kinase inhibits cAMP-induced differentiation in HL-60 leukemia cells without affecting phorbol ester effects. [PDF]

, 1990
Giampaolo Tortora, Timothy Clair, Yoon S. Cho‐Chung   +2 more
openalex   +1 more source

Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors

Nature Structural &Molecular Biology, 2010
K. Ojo, E. Larson, K. Keyloun, L. Castaneda, A. DeRocher, Krishna K Inampudi, Jessica E. Kim, T. Arakaki, R. C. Murphy, Li Zhang, A. Napuli, Dustin J Maly, C. Verlinde, F. Buckner, M. Parsons, W. Hol, E. Merritt, W. V. Voorhis   +17 more
semanticscholar   +1 more source

Statins induce monocytic differentiation in acute myeloid leukemia cells through the KLF4/DPYSL2A axis

FEBS Open Bio, EarlyView.
Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura, Kota Shoji, Michidai Nobe, Moe Ishikawa, Miu Tanaka, Akiko Okayama, Souichi Adachi, Hidemasa Matsuo   +7 more
wiley   +1 more source

Recent Advances in Structural Optimization of Quinazoline-Based Protein Kinase Inhibitors for Cancer Therapy (2021-Present). [PDF]

Molecules
Abdel-Mohsen HT, Anwar MM, Ahmed NS, Abd El-Karim SS, Abdelwahed SH.   +4 more
europepmc   +1 more source

Cyclic Peptides as Protein Kinase Inhibitors: Structure-Activity Relationship and Molecular Modeling. [PDF]

J Chem Inf Model, 2021
Sanner MF, Zoghebi K, Hanna S, Mozaffari S, Rahighi S, Tiwari RK, Parang K.   +6 more
europepmc   +1 more source

Inhibition of Protein Kinase-A by Overexpression of the Cloned Human Protein Kinase Inhibitor

, 1991
Steven R. Olsen, Michael D. Uhler
openalex   +1 more source

Inhibitors of protein kinase C prolong the falling phase of each free-calcium transient in a hormone-stimulated hepatocyte [PDF]

, 1990
A Sanchez-Bueno, C. Jane Dixon, N M Woods, Kevin Cuthbertson, P H Cobbold   +4 more
openalex   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source