Results 171 to 180 of about 1,314,106 (300)

Toll-Like Receptor- and Protein Kinase R-Induced Type I Interferon Sustains Infection of <i>Leishmania donovani</i> in Macrophages. [PDF]

Front Immunol, 2022
Dias BT, Goundry A, Vivarini AC, Costa TFR, Mottram JC, Lopes UG, Lima APCA.   +6 more
europepmc   +1 more source

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

Arthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp, Anne Horne, Borislav Mihov, Jill Drake, Janine Haslett, Peter Chapman, Daniel F. B. Wright, Christopher Frampton, Nicola Dalbeth   +8 more
wiley   +1 more source

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R [PDF]

, 2009
Christiane A. Opitz, Ulrike Litzenburger, Christian Lutz, Tobias V. Lanz, Isabel Tritschler, Alexandra Köppel, Eva Tolosa, M. Hoberg, Jan Anderl, Wilhelm K. Aicher, Michael Weller, Wolfgang Wick, Michael Platten   +12 more
openalex   +1 more source

Rapid adaptation to human protein kinase R by a unique genomic rearrangement in rhesus cytomegalovirus. [PDF]

PLoS Pathog, 2021
Child SJ, Greninger AL, Geballe AP.
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Hepatitis C Virus Blocks Interferon Effector Function by Inducing Protein Kinase R Phosphorylation [PDF]

, 2009
Urtzi Garaigorta, Francis V. Chisari
openalex   +1 more source

Coronavirus Endoribonuclease Ensures Efficient Viral Replication and Prevents Protein Kinase R Activation. [PDF]

J Virol, 2021
Zhao J, Sun L, Zhao Y, Feng D, Cheng J, Zhang G.   +5 more
europepmc   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Protein Kinase R Is Responsible for the Phosphorylation of eIF2α in Rotavirus Infection [PDF]

, 2010
Margarito Rojas, Carlos F. Arias, Susana López   +2 more
openalex   +1 more source

Activation of dsRNA-Dependent Protein Kinase R by MicroRNA-378 Sustains Metabolic Inflammation in Hepatic Insulin Resistance [PDF]

, 2021
Hao Wang, Yongyan Song, Yuxin Wu, Virender Kumar, Ram I. Mahato, Qiaozhu Su   +5 more
openalex   +1 more source