Computational analysis of regulatory regions in human protein kinases. [PDF]
Protein Sci, 2023 Pei J, Cong Q.
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Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers
Molecular and Cellular Biology, 1999 H. Schaeffer, M. J. Weber
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The role of circular RNAs in regulating cytokine signaling in cancer
FEBS Open Bio, EarlyView.Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi +4 more
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Identifying and evaluating understudied protein kinases using biological and chemical criteria. [PDF]
RSC Med ChemKoch S, Bajorath J.
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FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
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Molecular insight on the role of the phosphoinositide PIP3 in regulating the protein kinases Akt, PDK1, and BTK. [PDF]
Biochem Soc TransShaw AL, Burke JE.
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Protein Kinases and Neurodegenerative Diseases. [PDF]
Int J Mol Sci, 2023 Kawahata I, Fukunaga K.
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Phosphorylation of cardiac troponin by guanosine 3‘:5‘-monophosphate-dependent protein kinase.
, 1978 Donald Blumenthal +2 more
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Stimulation of uterine nonhistone protein phosphorylation and nuclear protein kinase activity by estradiol-17β [PDF]
, 1976 Michael E. Cohen, Lewis J. Kleinsmith
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Earthing effects on mitochondrial function: ATP production and ROS generation
FEBS Open Bio, EarlyView.In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
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