Results 221 to 230 of about 856,952 (362)
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó+7 more
wiley +1 more source
Identifying and evaluating understudied protein kinases using biological and chemical criteria. [PDF]
Koch S, Bajorath J.
europepmc +1 more source
Vesicular stomatitis virus deficient in protein kinase is infectious [PDF]
K. B. Tan, H. F. Clark
openalex +1 more source
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová+11 more
wiley +1 more source
Targeting JNK1/2 and P38 Mitogen-Activated Protein Kinases With Pazopanib Mitigates Bleomycin-Induced Lung Fibrosis. [PDF]
Abdelhady R+8 more
europepmc +1 more source
Direct detection of protein kinases on electropherograms [PDF]
Lorenzo A. Pinna+2 more
openalex +1 more source
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao+7 more
wiley +1 more source
Water-Based Pharmacophore Modeling in Kinase Inhibitor Design: A Case Study on Fyn and Lyn Protein Kinases. [PDF]
Ljubič M+3 more
europepmc +1 more source