Results 151 to 160 of about 914,048 (349)

ProteinGLUE multi-task benchmark suite for self-supervised protein modeling. [PDF]

Sci Rep, 2022
Capel H, Weiler R, Dijkstra M, Vleugels R, Bloem P, Feenstra KA.   +5 more
europepmc   +1 more source

Additional file 1 of Collectively encoding protein properties enriches protein language models

, 2022
Jingmin An, Xiaogang Weng
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Intra-Host Evolution During Relapsing Parvovirus B19 Infection in Immunocompromised Patients

Viruses
Background: Parvovirus B19 (B19V) can cause severe relapsing episodes of pure red cell aplasia in immunocompromised individuals, which are commonly treated with intravenous immunoglobulins (IVIGs).
Anne Russcher, Yassene Mohammed, Margriet E. M. Kraakman, Xavier Chow, Stijn T. Kok, Eric C. J. Claas, Manfred Wuhrer, Ann C. T. M. Vossen, Aloys C. M. Kroes, Jutte J. C. de Vries   +9 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

ModFlex: Towards Function Focused Protein Modeling. [PDF]

J Mol Biol, 2021
Sedova M, Jaroszewski L, Iyer M, Li Z, Godzik A.   +4 more
europepmc   +1 more source

Molecular Docking Screens Using Comparative Models of Proteins

, 2009
Hao Fan, John J. Irwin, Benjamin Webb, G. Klebe, Brian K. Shoichet, Andrej Săli   +5 more
openalex   +1 more source

Protein folding: Funnel model revised

Computational and Structural Biotechnology Journal
The spatial structure of proteins, largely determined by their amino acid sequences, is also dependent on the environmental conditions under which the folding process takes place. In aqueous environments, exposure of polar amino acids is the driving factor, whereas protein stabilization in amphipathic membranes requires exposure to hydrophobic residues.
Roterman-Konieczna, Irena, Slupina, Mateusz, Konieczny, Leszek   +2 more
openaire   +3 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Computational protein modeling and the next viral pandemic. [PDF]

Nat Methods, 2021
Narykov O, Srinivasan S, Korkin D.
europepmc   +1 more source