Results 241 to 250 of about 914,048 (349)

Protein modeling and clinical description of a novel in-frame GLB1 deletion causing GM1 gangliosidosis type II. [PDF]

Mol Genet Genomic Med, 2018
Richter JE, Zimmermann MT, Blackburn PR, Mohammad AN, Klee EW, Pollard LM, Macmurdo CF, Atwal PS, Caulfield TR.   +8 more
europepmc   +1 more source

Advancing virulence factor prediction using protein language models [PDF]

Yitong Liu, Xin Cao, Jiani Li, Tao Li, Juanjuan Li, Xiang Ma, Xue Chi, Yanqiong Tang, Zhu Liu, Hong Li   +9 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Identification and Visualization of Functionally Important Domains and Residues in Herpes Simplex Virus Glycoprotein K(gK) Using a Combination of Phylogenetics and Protein Modeling. [PDF]

Sci Rep, 2019
Rider PJF, Coghill LM, Naderi M, Brown JM, Brylinski M, Kousoulas KG.   +5 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Convert your favorite protein modeling program into a mutation predictor: "MODICT". [PDF]

BMC Bioinformatics, 2016
Tanyalcin I, Stouffs K, Daneels D, Al Assaf C, Lissens W, Jansen A, Gheldof A.   +6 more
europepmc   +1 more source

DeepHVI: A multimodal deep learning framework for predicting human-virus protein-protein interactions using protein language models

X. F. Wang, Junyu Luo, Xiyang Cai, Ruibin Liu, Yixue Li, Chitin Hon   +5 more
openalex   +1 more source

Lumry−Eyring Nucleated-Polymerization Model of Protein Aggregation Kinetics. 2. Competing Growth via Condensation and Chain Polymerization

, 2009
Yi Li, Christopher J. Roberts
openalex   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Bam: A Deep Learning Model for Protein-Ligand Affinity Prediction

Jianchun Zhang, Ke Wan, Jiangfeng Sun
openalex   +1 more source