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Protein phosphatases are pest containing proteins
IUBMB Life, 1997AbstractProtein phosphatases are required for removing phosphoryl groups in proteins involved in many physiological processes. Investigation of these enzymes for regions rich in proline (P), glutamic acid (E), serine (S) and threonine (T), called PEST regions showed that greater than 85% of the phosphatases investigated contained these regions.
A V, Gomes, J A, Barnes
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Protein Phosphatases in Plants
Annual Review of Plant Biology, 2003Phosphorylation and dephosphorylation of a protein often serve as an “on-and-off” switch in the regulation of cellular activities. Recent studies demonstrate the involvement of protein phosphorylation in almost all signaling pathways in plants. A significant portion of the sequenced Arabidopsis genome encodes protein kinases and protein phosphatases ...
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N -Phosphoarginine Phosphatase (17 kDa) and Alkaline Phosphatase as Protein Arginine Phosphatases
Journal of Biochemistry, 1996Seven synthetic polymers, (Glu4, Tyr)n, (Arg)n, (Arg, Pro, Thr)n, (Arg-Gly-Glu)6, (Arg-Gly-Phe)6, (Glu-Arg-Gly-Phe)5, and (Ala-Leu-Arg-Arg-Ile-Arg-Gly-Glu-Arg)2, were treated with phosphoryl chloride to phosphorylate their Tyr, Thr, and Arg residues. Protamines and histones were phosphorylated similarly.
A, Kumon +4 more
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Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2013
The current work briefly reviews what is currently known about protein phosphorylation on arginine, lysine and histidine residues, where PN bonds are formed, and the protein kinases that catalyze these reactions. Relatively little is understood about protein arginine and lysine kinases and the role of phosphorylation of these residues in cellular ...
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The current work briefly reviews what is currently known about protein phosphorylation on arginine, lysine and histidine residues, where PN bonds are formed, and the protein kinases that catalyze these reactions. Relatively little is understood about protein arginine and lysine kinases and the role of phosphorylation of these residues in cellular ...
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Viral protein kinases and protein phosphatases
Pharmacology & Therapeutics, 1993Certain large DNA viruses (e.g. herpesviruses and poxviruses) encode proteins related to cellular protein-serine/threonine kinases, and Hepatitis B virus and vesicular stomatitis virus may encode structurally different protein kinases. Other viruses activate cellular protein kinases, e.g. interferon-induced eukaryotic initiation factor-2 kinase, growth
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Targeting protein phosphatases in cancer immunotherapy and autoimmune disorders
Nature Reviews Drug Discovery, 2023Nunzio Bottini
exaly