Results 201 to 210 of about 7,148,227 (413)

A pea homologue of human DNA helicase I is localized within the dense fibrillar component of the nucleolus and stimulated by phosphorylation with CK2 and cdc2 protein kinases [PDF]

, 2001
Narendra Tuteja, Alison F. Beven, Peter Shaw, Renu Tuteja   +3 more
openalex   +1 more source

THE ENZYMATIC PHOSPHORYLATION OF PROTEINS

Journal of Biological Chemistry, 1954
G, BURNETT, E P, KENNEDY
openaire   +2 more sources

Evolution of protein phosphorylation across 18 fungal species

Science, 2016
R. A. Studer, R. Rodríguez-Mias, Kelsey M. Haas, Joanne I. Hsu, Cristina Viéitez, Carme Solé, D. Swaney, Lindsay B. Stanford, Ivan Liachko, René Böttcher, Maitreya J. Dunham, Eulàlia de Nadal, F. Posas, P. Beltrão, J. Villén   +14 more
semanticscholar   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Characterization of the interleukin‐1‐induced tyrosine phosphorylation of a 41‐kDa plasma membrane protein of the human tumor cell line K 562 [PDF]

, 1989
Michael U. Martin, David H. Lovett, Márta Szamel, Klaus Resch   +3 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

TRPM7 Regulates Myosin IIA Filament Stability and Protein Localization by Heavy Chain Phosphorylation

, 2008
Kristopher Clark, Jeroen Middelbeek, Edwin Lasonder, Natalya G. Dulyaninova, Nick Morrice, Alexey G. Ryazanov, Anne R. Bresnick, Carl G. Figdor, Frank N. van Leeuwen   +8 more
openalex   +1 more source

Middle-down proteomics reveals dense sites of methylation and phosphorylation in arginine-rich RNA-binding proteins [PDF]

, 2019
Sean R. Kundinger, Isaac Bishof, Eric B. Dammer, Duc M. Duong, Nicholas T. Seyfried   +4 more
openalex   +1 more source