Results 211 to 220 of about 1,406,847 (366)

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Multimodal knowledge expansion widget powered by plant protein phosphorylation database and ChatGPT. [PDF]

Front Bioinform
Xu C, Yu Y, Khadakkar G, Xie J, Xu D, Yao Q.   +5 more
europepmc   +1 more source

Effects of WY-14,643 on the phosphorylation and activation of AMP-dependent protein kinase

, 2009
Suthat Liangpunsakul, Sung-Eun Wou, Kevin D. Wineinger, Yan Zeng, I. Cyganek, Hiremagalur N. Jayaram, David W. Crabb   +6 more
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Protocol to quantify protein phosphorylation in mouse extended pluripotent stem cell-derived blastoids. [PDF]

STAR Protoc
Xiao T, Luo Y, Yu Y.
europepmc   +1 more source

The Sites of Phosphorylation by Protein Kinase C and an Intact SH2 Domain Are Required for the Enhanced Response to β-Adrenergic Agonists in Cells Overexpressing c-src

, 1993
Julie S. Moyers, Amy H. Bouton, Sarah J. Parsons   +2 more
openalex   +2 more sources

Amino acid sequence of in vivo phosphorylation sites in the main intrinsic protein (MIP) of lens membranes [PDF]

, 1990
Paul D. Lampe, Ross G. Johnson
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Protein phosphorylation networks in Baylisascaris procyonis revealed by phosphoproteomic analysis. [PDF]

Parasit Vectors
Meng Q, Li Z, Qiu Q, Chen S, Gong H, Tan X, Liu X, Chen Z, Liu W.   +8 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source