Results 211 to 220 of about 7,148,227 (413)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Assessing the relation between protein phosphorylation, AlphaFold3 models, and conformational variability. [PDF]

Protein Sci
Ramasamy P, Zuallaert J, Martens L, Vranken WF.   +3 more
europepmc   +1 more source

Binding and Phosphorylation of a Novel Male Germ Cell-specific cGMP-dependent Protein Kinase-anchoring Protein by cGMP-dependent Protein Kinase Iα

, 2000
Keizo Yuasa, Kenji Omori, Noriyuki Yanaka   +2 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Global comparative structural analysis of responses to protein phosphorylation. [PDF]

Nat Commun
Correa Marrero M, Mello VH, Sartori P, Beltrao P.   +3 more
europepmc   +1 more source

Phosphorylation of the Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein

, 2002
Sarah K. Wootton, Raymond R. R. Rowland, Dongwan Yoo   +2 more
openalex   +1 more source

Caveolae Differentially Control Phosphorylation of Sarcoplasmic Reticular Proteins Following β2 Adrenoceptor Stimulation in the Adult Cardiac Myocyte [PDF]

, 2010
D. MacDougall, John Colyer, Sarah Calaghan   +2 more
openalex   +1 more source

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

Cell, 2010
Edward L. Huttlin, Mark P. Jedrychowski, Joshua E. Elias, T. Goswami, R. Rad, S. Beausoleil, J. Villén, W. Haas, M. Sowa, S. Gygi   +9 more
semanticscholar   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

A distinct PP2A subunit regulates local protein phosphorylation at the axon initial segment. [PDF]

Nat Commun
Anderson AP, Kim S, Melton AJ, Ding X, Zhang W, Saltzman AB, Malovannaya A, Rasband MN, Gao Y.   +8 more
europepmc   +1 more source