Results 221 to 230 of about 7,148,227 (413)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Multimodal knowledge expansion widget powered by plant protein phosphorylation database and ChatGPT. [PDF]

Front Bioinform
Xu C, Yu Y, Khadakkar G, Xie J, Xu D, Yao Q.   +5 more
europepmc   +1 more source

Inhibition of Heat Shock Induction of Heat Shock Protein 70 and Enhancement of Heat Shock Protein 27 Phosphorylation by Quercetin Derivatives

, 2009
Rongsheng E. Wang, Jeffrey L.-F. Kao, Carolyn A. Hilliard, Raj K. Pandita, Joseph L. Roti Roti, Clayton R. Hunt, John‐Stephen Taylor   +6 more
openalex   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Protocol to quantify protein phosphorylation in mouse extended pluripotent stem cell-derived blastoids. [PDF]

STAR Protoc
Xiao T, Luo Y, Yu Y.
europepmc   +1 more source

Differential expression and phosphorylation of distinct STAT3 proteins during granulocytic differentiation [PDF]

, 2002
Diane L. Hevehan, William M. Miller, Eleftherios T. Papoutsakis   +2 more
openalex   +1 more source

Structural Analysis of Mammalian Protein Phosphorylation at a Proteome Level

, 2021
Altuğ Kamacıoğlu, Nurcan Tunçbağ, Nurhan Özlü   +2 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Protein phosphorylation networks in Baylisascaris procyonis revealed by phosphoproteomic analysis. [PDF]

Parasit Vectors
Meng Q, Li Z, Qiu Q, Chen S, Gong H, Tan X, Liu X, Chen Z, Liu W.   +8 more
europepmc   +1 more source

Regulation of Erythropoietin-induced STAT Serine Phosphorylation by Distinct Mitogen-activated Protein Kinases [PDF]

, 2002
Rizwan Haq, Adrienne Halupa, Bryan K. Beattie, Jacqueline M. Mason, Brent W. Zanke, Dwayne L. Barber   +5 more
openalex   +1 more source