Results 71 to 80 of about 6,431,938 (269)
Protein phosphorylation in chloroplasts – a survey of phosphorylation targets [PDF]
Journal of Experimental Botany, 2016 The development of new software tools, improved mass spectrometry equipment, a suite of optimized scan types, and better-quality phosphopeptide affinity capture have paved the way for an explosion of mass spectrometry data on phosphopeptides. Because phosphoproteomics achieves good sensitivity, most studies use complete cell extracts for phosphopeptide
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The importance of intrinsic disorder for protein phosphorylation.
Nucleic Acids Research, 2004 Reversible protein phosphorylation provides a major regulatory mechanism in eukaryotic cells. Due to the high variability of amino acid residues flanking a relatively limited number of experimentally identified phosphorylation sites, reliable prediction ...
L. Iakoucheva +7 more
semanticscholar +1 more source
Symposia on Plant (Protein) Phosphorylation [PDF]
Frontiers in Plant Science, 2012 From September 14-16, 2011 the twelfth symposium on Plant Protein Phosphorylation was held in Tübingen, Germany. The topic is as broad as the name suggests and covers all aspects of this important means of protein modification in plants. I have had the pleasure of attending the 2007 and the 2011 symposia.
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Mechanism of TNFα-induced downregulation of salt-inducible kinase 2 in adipocytes
Scientific Reports, 2023 Salt-inducible kinase 2 (SIK2) is highly expressed in white adipocytes, but downregulated in individuals with obesity and insulin resistance. These conditions are often associated with a low-grade inflammation in adipose tissue.
Magdaléna Vaváková +3 more
doaj +1 more source
Dynamics of allosteric action in multisite protein modification [PDF]
, 2006 Protein functions in cells may be activated or modified by the attachment of several kinds of chemical groups. While protein phosphorylation, i.e. the attachment of a phosphoryl (PO$_3^-$) group, is the most studied form of protein modification, and is known to regulate the functions of many proteins, protein behavior can also be modified by ...
arxiv +1 more source
Turnover of protein phosphorylation evolving under stabilizing selection
Frontiers in Genetics, 2014 Most proteins are regulated by posttranslational modifications and changes in these modifications contribute to evolutionary changes as well as to human diseases.
C. Landry +3 more
semanticscholar +1 more source
Protein phosphorylation in stomatal movement
Plant Signalling & Behavior, 2014 As research progresses on how guard cells perceive and transduce environmental cues to regulate stomatal movement, plant biologists are discovering key roles of protein phosphorylation.
Tong Zhang, Sixue Chen, A. Harmon
semanticscholar +1 more source
Protein Phosphorylation and Neuronal Function [PDF]
Journal of Neurochemistry, 1985 Studies in the past several years have provided direct evidence that protein phosphorylation is involved in the regulation of neuronal function. Electrophysiological experiments have demonstrated that three distinct classes of protein kinases, i.e., cyclic AMP-dependent protein kinase, protein kinase C, and CaM kinase II, modulate physiological ...
Paul Greengard +2 more
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N-site phosphorylation systems with 2N-1 steady states [PDF]
arXiv, 2013 Multisite protein phosphorylation plays a prominent role in intracellular processes like signal transduction, cell-cycle control and nuclear signal integration. Many proteins are phosphorylated in a sequential and distributive way at more than one phosphorylation site.
arxiv
Characterization of Phosphorylated Tau-Microtubule complex with Molecular Dynamics (MD) simulation [PDF]
arXiv, 2023 Alzheimer's Disease (AD), a neurodegenerative disorder, is reported as one of the most severe health and socioeconomic problems in current public health. Tau proteins are assumed to be a crucial driving factor of AD that detach from microtubules (MT) and accumulate as neurotoxic aggregates in the brains of AD patients.
arxiv