Results 181 to 190 of about 369,882 (213)
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PROTEOMICS, 2003
AbstractPost‐translational modification of the antiphagocytic M1 protein of Streptococcus pyogenes can influence its binding properties for human immunoglobulin G subclasses and its invasive potential. Current methods of monitoring this modification event involve N‐terminal sequencing and are cumbersome, slow and not amenable to routine analysis.
Terence G Romer, Michael D. P. Boyle
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AbstractPost‐translational modification of the antiphagocytic M1 protein of Streptococcus pyogenes can influence its binding properties for human immunoglobulin G subclasses and its invasive potential. Current methods of monitoring this modification event involve N‐terminal sequencing and are cumbersome, slow and not amenable to routine analysis.
Terence G Romer, Michael D. P. Boyle
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Journal of Theoretical Biology, 1984
A mathematical model is presented that describes first order degradation and post-translational processing of proteins in non-growing and exponentially growing cells. The model applies to proteins that are substrates or products of processing. General equations are presented that can be applied to many different experimental protocols.
Raymond D. Mosteller, Bruce E. Goldstein
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A mathematical model is presented that describes first order degradation and post-translational processing of proteins in non-growing and exponentially growing cells. The model applies to proteins that are substrates or products of processing. General equations are presented that can be applied to many different experimental protocols.
Raymond D. Mosteller, Bruce E. Goldstein
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Archives of Biochemistry and Biophysics, 1993
The two early endosome-associated rab GTP-binding proteins, rab4 and rab5, are suggested to regulate endocytosis. In this report, we examined post-translational processing and membrane association of the two rab proteins. Human rab4 and rab5 were expressed in chicken embryo fibroblasts using a Sindbis virus expression vector.
P.D. Stahl, Guangpu Li
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The two early endosome-associated rab GTP-binding proteins, rab4 and rab5, are suggested to regulate endocytosis. In this report, we examined post-translational processing and membrane association of the two rab proteins. Human rab4 and rab5 were expressed in chicken embryo fibroblasts using a Sindbis virus expression vector.
P.D. Stahl, Guangpu Li
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Engineering Post-Translational Processing of Recombinant Proteins Produced in Insect Cell Culture
2000A number of host organisms are used today to facilitate the production of recombinant proteins. Recombinant proteins are produced in cultures derived from both prokaryotic and eukaryotic sources. The proteins obtained from these sources are used in a wide range of applications including diagnostics, structure-function studies, therapeutics, and ...
E. Ailor, M. J. Betenbaugh
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Molecular and Biochemical Parasitology, 2007
The C-terminal "CaaX"-motif-containing proteins usually undergo three sequential post-translational processing steps: (1) attachment of a prenyl group to the cysteine residue; (2) proteolytic removal of the last three amino acids "aaX"; (3) methyl esterification of the exposed alpha-carboxyl group of the prenyl-cysteine residue.
James G. Bollinger +7 more
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The C-terminal "CaaX"-motif-containing proteins usually undergo three sequential post-translational processing steps: (1) attachment of a prenyl group to the cysteine residue; (2) proteolytic removal of the last three amino acids "aaX"; (3) methyl esterification of the exposed alpha-carboxyl group of the prenyl-cysteine residue.
James G. Bollinger +7 more
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Biological Psychiatry, 1989
236 Alzheimer’s disease (AD) is characterized by extensive cholinergic denervation in both cortex and hippocampus. However, cholinergic therapies are of limited value. We investigated choline@ mechanisms in hippocampus which was denervated by a fimbriafomix lesion. Denervated pyramidal cells were found to be hypersensitive to carbachol, responding to a
John P. Anderson +3 more
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236 Alzheimer’s disease (AD) is characterized by extensive cholinergic denervation in both cortex and hippocampus. However, cholinergic therapies are of limited value. We investigated choline@ mechanisms in hippocampus which was denervated by a fimbriafomix lesion. Denervated pyramidal cells were found to be hypersensitive to carbachol, responding to a
John P. Anderson +3 more
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Post-Translational Processing of Surfactant Protein-C Proprotein
American Journal of Respiratory Cell and Molecular Biology, 2001Rat surfactant protein (SP)-C is a 3.7-kD hydrophobic lung-specific protein generated from proteolytic processing of a 21-kD propeptide (SP-C(21)). We have demonstrated that initial post-translational processing of SP-C(21) involves two cleavages of the COOH-terminus (Beers and colleagues, J. Biol. Chem. 1994;269:20,318--20,328).
Giuseppe G. Pietra +6 more
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The contemporary management of cancers of the sinonasal tract in adults
Ca-A Cancer Journal for Clinicians, 2023Rajat Thawani
exaly
Post-translational processing of ras proteins
Biochemical Society Transactions, 1989openaire +3 more sources