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Post-translational Modifications of the Protein Termini [PDF]
Frontiers in Cell and Developmental Biology, 2021 Post-translational modifications (PTM) involve enzyme-mediated covalent addition of functional groups to proteins during or after synthesis. These modifications greatly increase biological complexity and are responsible for orders of magnitude change ...
Li Chen, Anna Kashina
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Post-translational modifications in rosacea [PDF]
Frontiers in ImmunologyRosacea is a chronic inflammatory skin disease that primarily affects the central facial region, including the cheeks, nose, chin, and forehead. Its clinical features include episodic flushing, persistent erythema, telangiectasia, papulopustular lesions,
Xuting Zhang +4 more
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Post‐Translational Modifications in Animal Circadian Clocks [PDF]
Advanced ScienceThe circadian clock is a fundamental biological system that synchronizes behavioral and physiological processes such as metabolism and immunity with the 24 h day‐night cycle.
Xianhui Liu, Yong Zhang
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Post-translational modifications in Neuroimmune cells during neuroinflammation: integrated regulatory networks and therapeutic opportunities [PDF]
Biology DirectNeuroinflammation represents a common pathological mechanism underlying a wide range of central nervous system (CNS) disorders, encompassing neurodegenerative disorders (NDDs), ischemic stroke (IS), traumatic brain injury (TBI), and demyelinating ...
Wei Li +8 more
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Sirtuin Oxidative Post-translational Modifications
Frontiers in Physiology, 2021 Increased sirtuin deacylase activity is correlated with increased lifespan and healthspan in eukaryotes. Conversely, decreased sirtuin deacylase activity is correlated with increased susceptibility to aging-related diseases.
Kelsey S. Kalous +2 more
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Post-Translational Modifications of Extracellular Proteasome
Molecules, 2020 The ubiquitin-proteasome system (UPS) is one of the major protein degradation pathways in eukaryotic cells. Abnormal functioning of this system has been observed in cancer and neurological diseases.
Anna S. Tsimokha +4 more
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Post-Translational Modifications That Drive Prostate Cancer Progression
Biomolecules, 2021 While a protein primary structure is determined by genetic code, its specific functional form is mostly achieved in a dynamic interplay that includes actions of many enzymes involved in post-translational modifications.
Ivana Samaržija
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Post-Translational Modifications Aid Archaeal Survival
Biomolecules, 2020 Since the pioneering work of Carl Woese, Archaea have fascinated biologists of almost all areas given their unique evolutionary status, wide distribution, high diversity, and ability to grow in special environments.
Ping Gong +4 more
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“NO” Time in Fear Response: Possible Implication of Nitric-Oxide-Related Mechanisms in PTSD
Molecules, 2023 Post-traumatic stress disorder (PTSD) is a psychiatric condition characterized by persistent fear responses and altered neurotransmitter functioning due to traumatic experiences.
Mariana G. Fronza +4 more
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Phosphorylation of Kindlins and the Control of Integrin Function
Cells, 2021 Integrins serve as conduits for the transmission of information between cells and their extracellular environment. Signaling across integrins is bidirectional, transducing both inside-out and outside-signaling.
Katarzyna Bialkowska +2 more
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