Results 1 to 10 of about 469,548 (293)

Editorial: Bacterial Post-translational Modifications

Frontiers in Microbiology, 2022
International ...
Valerie J. Carabetta, Julie Hardouin, Julie Hardouin   +2 more
doaj   +5 more sources

PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data [PDF]

, 2014
Interactions among transcriptional factors (TFs), cofactors and other proteins or enzymes can affect transcriptional regulatory capabilities of eukaryotic organisms. Post-translational modifications (PTMs) cooperate with TFs and epigenetic alterations to
Boheler, KR, Deng, Y, Guan, D, Qin, J, Shao, J, Wang, JJ, Wang, P, Yan, B, Zhao, Z   +8 more
core   +1 more source

Motifs tree: a new method for predicting post-translational modifications [PDF]

, 2017
Motivation: Post-translational modifications (PTMs) are important steps in the maturation of proteins. Several models exist to predict specific PTMs, from manually detected patterns to machine learning methods.
Charpilloz, Christophe, Chopard, Bastien, Falcone, Jean-Luc, Veuthey, Anne-Lise   +3 more
core  

DNA methylation dynamics in aging: How far are we from understanding the mechanisms? [PDF]

, 2018
DNA methylation is currently the most promising molecular marker for monitoring aging and predicting life expectancy. However, the mechanisms underlying age-related DNA methylation changes remain mostly undiscovered.Here we discuss the current knowledge ...
Caiafa, Paola, Ciccarone, Fabio, Tagliatesta, Stefano, Zampieri, Michele   +3 more
core   +1 more source

Implication of protein post translational modifications in gastric cancer

Frontiers in Cell and Developmental Biology
Gastric cancer (GC) is one of the most common and highly lethal malignant tumors worldwide, and its occurrence and development are regulated by multiple molecular mechanisms.
Houji Song, Mingze Zhang, Chengwang Guo, Xi Guo, Yuqi Ma, Yuntao Ma, Yuntao Ma   +6 more
doaj   +1 more source

Roles of Post-translational Modifications in Spinocerebellar Ataxias

Frontiers in Cellular Neuroscience, 2018
Post-translational modifications (PTMs), including phosphorylation, acetylation, ubiquitination, SUMOylation, etc., of proteins can modulate protein properties such as intracellular distribution, activity, stability, aggregation, and interactions ...
Linlin Wan, Keqin Xu, Zhao Chen, Beisha Tang, Beisha Tang, Beisha Tang, Beisha Tang, Beisha Tang, Beisha Tang, Beisha Tang, Hong Jiang, Hong Jiang, Hong Jiang, Hong Jiang, Hong Jiang   +14 more
doaj   +1 more source

Elucidating Host-Pathogen Interactions Based on Post-Translational Modifications Using Proteomics Approaches [PDF]

, 2015
Microbes with the capability to survive in the host tissue and efficiently subvert its innate immune responses can cause various health hazards. There is an inherent need to understand microbial infection patterns and mechanisms in order to develop ...
Jers, Carsten, Mijakovic, Ivan, Ravikumar, Vaishnavi   +2 more
core   +1 more source

Mass spectrometry-based profiling of single-cell histone post-translational modifications to dissect chromatin heterogeneity

Nature Communications
Single-cell proteomics confidently quantifies cellular heterogeneity, however quantification of post-translational modifications, such as those deposited on histone proteins, remains elusive.
Ronald Cutler, Laura Corveleyn, Claudia Ctortecka, Francesca LiCausi, Joshua Cantlon, Alvaro Sebastian Vaca Jacome, Dieter Deforce, Jan Vijg, Maarten Dhaenens, Malvina Papanastasiou, Steven A. Carr, Simone Sidoli   +11 more
doaj   +1 more source

ProteomeScout: A repository and analysis resource for post-translational modifications and proteins [PDF]

, 2014
ProteomeScout (https://proteomescout.wustl.edu) is a resource for the study of proteins and their post-translational modifications (PTMs) consisting of a database of PTMs, a repository for experimental data, an analysis suite for PTM experiments, and a ...
Alex S. Holehouse, Barrett, Benjamini, Benson, Binns, Cock, Craveur, Dinkel, Finn, Fujita, Gnad, Griss, Guo, Gupta, Hornbeck, Hsu, Iwai, Joughin, Karolchik, Kristen M. Naegle, Lu, Matthew K. Matlock, Minguez, Moore, Naegle, Naegle, Naegle, NCBI Resource Coordinators, Obenauer, Prasad, Rose, Schmelzle, Sherry, Stockinger, Su, The Gene Ontology Consortium, The UniProt Consortium, Villaveces, Wagner, Walt, Wein, Witze, Wolf-Yadlin   +42 more
core   +3 more sources

Post-translational regulation of an Aplysia glutamate transporter during long-term facilitation. [PDF]

, 2009
Regulation of glutamate transporters accompanies plasticity of some glutamatergic synapses. The regulation of glutamate uptake at the Aplysia sensorimotor synapse during long-term facilitation (LTF) was investigated.
Byrne, John H, Collado, Maria Sol, Eskin, Arnold, Fioravante, Diasinou, Khabour, Omar   +4 more
core   +1 more source