Results 1 to 10 of about 43,903 (286)

Systems Level Analysis of Histone H3 Post-translational Modifications (PTMs) Reveals Features of PTM Crosstalk in Chromatin Regulation. [PDF]

Mol Cell Proteomics, 2016
Histones are abundant chromatin constituents carrying numerous post-translational modifications (PTMs). Such PTMs mediate a variety of biological functions, including recruitment of enzymatic readers, writers and erasers that modulate DNA replication, transcription and repair. Individual histone molecules contain multiple coexisting PTMs, some of which
Schwämmle V, Sidoli S, Ruminowicz C, Wu X, Lee CF, Helin K, Jensen ON.   +6 more
europepmc   +5 more sources

Current Technologies Unraveling the Significance of Post-Translational Modifications (PTMs) as Crucial Players in Neurodegeneration. [PDF]

Biomolecules
Neurodegenerative disorders, such as Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease, are identified and characterized by the progressive loss of neurons and neuronal dysfunction, resulting in cognitive and motor impairment.
Zafar S, Fatima SI, Schmitz M, Zerr I.
europepmc   +6 more sources

Adaptable Alchemy: Exploring the Flexibility of Specialized Metabolites to Environmental Perturbations Through Post-Translational Modifications (PTMs). [PDF]

Plants (Basel)
Plants are subjected to various stresses during the growth process, including biotic stresses, as well as abiotic stresses such as temperature, drought, salt, and heavy metals. To cope with these biotic and abiotic adversities, plants have evolved complex regulatory mechanisms during their long-term environmental adaptations.
Cimmino L, Staiti A, Carputo D, Docimo T, D'Amelia V, Aversano R.   +5 more
europepmc   +6 more sources

HSP90 proteins in the scenario of tumor complexity [PDF]

, 2017
Rasola, Andrea
core   +1 more source

PubMed-Scale Event Extraction for Post-Translational Modifications, Epigenetics and Protein Structural Relations [PDF]

, 2012
Ananiadou, S, Björne, J, Ginter, F, Ohta, T, Pyysalo, S, Salakoski, T, Van de Peer, Y, Van Landeghem, S   +7 more
core  

Metabolic and post-translational modifications in sepsis-associated immune dysfunction: a conceptual framework. [PDF]

Front Immunol
Xu M, Zhang Z, Zhu M, Zhang S, Deng J, Du Z, Wang Z, Zhao H, Qiu Z.   +8 more
europepmc   +1 more source

Diabetes-Driven Post-Translational Remodeling in Pancreatic Ductal Adenocarcinoma. [PDF]

Cancers (Basel)
Kavyashree S, Harithpriya K, Ganesan K, Ramkumar KM.   +3 more
europepmc   +1 more source

Dual Regulation of Post-Translational Modification of Proteins: Bottlenecks and Breakthroughs in NK Cell Therapy for Glioblastoma

International Journal of General Medicine
Yushu Liu, Qingya Qiu, Hui Deng, Ping Song, Jiarui Bu, Mengxian Zhang Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of ChinaCorrespondence: Mengxian Zhang,
Liu Y, Qiu Q, Deng H, Song P, Bu J, Zhang M   +5 more
doaj  

A Multi-omics PTM Atlas Reveals Key Insights into Metabolic Reprogramming in Colorectal Cancer. [PDF]

Cancer Genomics Proteomics
Li T, Dong J, Zhang Y, Hao E, DU J, Feng M, Zhu F, Qin J, Zhang W, Dai Y.   +9 more
europepmc   +1 more source

How post-translational modifications in pathogenic fungi inform pathogenesis and immune responses. [PDF]

PLoS Pathog
Sahu SR, Specht CA, Levitz SM.
europepmc   +1 more source