Post-Translational Modifications in Atopic Dermatitis: Current Research and Clinical Relevance
Frontiers in Cell and Developmental Biology, 2022 Atopic dermatitis (AD) is a chronic and relapsing cutaneous disorder characterized by compromised immune system, excessive inflammation, and skin barrier disruption.
Xin Ma +17 more
doaj +1 more source
Adaptable Alchemy: Exploring the Flexibility of Specialized Metabolites to Environmental Perturbations Through Post-Translational Modifications (PTMs). [PDF]
Plants (Basel)Plants are subjected to various stresses during the growth process, including biotic stresses, as well as abiotic stresses such as temperature, drought, salt, and heavy metals. To cope with these biotic and abiotic adversities, plants have evolved complex regulatory mechanisms during their long-term environmental adaptations.
Cimmino L +5 more
europepmc +6 more sources
Investigation of post-translational modifications in type 2 diabetes
Clinical Proteomics, 2018 The investigation of post-translational modifications (PTMs) plays an important role for the study of type 2 diabetes. The importance of PTMs has been realized with the advancement of analytical techniques.
Bhaswati Chatterjee, Suman S. Thakur
doaj +1 more source
Peptidomics analysis of potato protein hydrolysates: post-translational modifications and peptide hydrophobicity [PDF]
, 2017 Post-translational modifications (PTMs) often occur in proteins and play a regulatory role in protein function. However, the role of PTMs in food-derived peptides remains largely unknown.
Shixiang Yao +3 more
core +2 more sources
Post-Translational Modification (PTM) Proteomics: Challenges and Perspectives [PDF]
Modern Chemistry & Applications, 2013 Copyright: © 2013 Darie CC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
openaire +1 more source
Vienna-PTM web server: a toolkit for MD simulations of protein post-translational modifications [PDF]
Nucleic Acids Research, 2013 Post-translational modifications (PTMs) play a key role in numerous cellular processes by directly affecting structure, dynamics and interaction networks of target proteins. Despite their importance, our understanding of protein PTMs at the atomistic level is still largely incomplete.
Christian Margreitter +2 more
openaire +4 more sources
PTM-Shepherd: analysis and summarization of post-translational and chemical modifications from open search results [PDF]
Molecular & Cellular Proteomics, 2020 ABSTRACT Open searching has proven to be an effective strategy for identifying both known and unknown modifications in shotgun proteomics experiments. Rather than being limited to a small set of user-specified modifications, open searches identify peptides with any mass shift that may correspond to a single modification or a combination
Daniel J. Geiszler +5 more
openaire +4 more sources
Histone H1 Post-Translational Modifications: Update and Future Perspectives [PDF]
, 2020 Histone H1 is the most variable histone and its role at the epigenetic level is less characterized than that of core histones. In vertebrates, H1 is a multigene family, which can encode up to 11 subtypes.
Marta Andrés +9 more
core +1 more source
Novel Post-translational Modifications in Human Serum Albumin
, 2022 Aim: This study aims to identify novel post-translational modifications in human serum albumin by mass spectrometry. Background: Serum albumin is the most abundant protein in plasma, has many physiological functions, and is in contact with most of the ...
Kannan, Surya +2 more
core +1 more source
Mechanisms of SOD1 regulation by post-translational modifications
Redox Biology, 2019 SOD1 is commonly known for its ROS scavenging activity, but recent work has uncovered additional roles in modulating metabolism, maintaining redox balance, and regulating transcription.
C.J. Banks, J.L. Andersen
doaj +1 more source