RECENT ADVANCES IN POST-TRANSLATIONAL REGULATION OF PLANT DEFENSE RESPONSES BEYOND PHOSPHORYLATION [PDF]
Journal of Plant Development, 2021 During plant-microbe interactions, plant immune signaling relies significantly on post-translational modifications (PTMs) to induce rapid downstream changes.
Tim XING, Ziwei GUO
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Functional Regulation of Hsp70 Allostery by Post‐Translational Modifications (PTMs)
The FASEB Journal, 2020 The 70‐kDa heat shock proteins (Hsp70s) perform critical functions in the protein homeostasis network, such as assisting nascent chain folding, preventing protein misfolding and aggregation, facilitating assembly of complexes, and driving protein translocation.
Wenli Meng +2 more
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Post-Translational Modifications in Atopic Dermatitis: Current Research and Clinical Relevance
Frontiers in Cell and Developmental Biology, 2022 Atopic dermatitis (AD) is a chronic and relapsing cutaneous disorder characterized by compromised immune system, excessive inflammation, and skin barrier disruption.
Xin Ma +17 more
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Adaptable Alchemy: Exploring the Flexibility of Specialized Metabolites to Environmental Perturbations Through Post-Translational Modifications (PTMs). [PDF]
Plants (Basel)Plants are subjected to various stresses during the growth process, including biotic stresses, as well as abiotic stresses such as temperature, drought, salt, and heavy metals. To cope with these biotic and abiotic adversities, plants have evolved complex regulatory mechanisms during their long-term environmental adaptations.
Cimmino L +5 more
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Investigation of post-translational modifications in type 2 diabetes
Clinical Proteomics, 2018 The investigation of post-translational modifications (PTMs) plays an important role for the study of type 2 diabetes. The importance of PTMs has been realized with the advancement of analytical techniques.
Bhaswati Chatterjee, Suman S. Thakur
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Post-Translational Modification (PTM) Proteomics: Challenges and Perspectives [PDF]
Modern Chemistry & Applications, 2013 Copyright: © 2013 Darie CC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Vienna-PTM web server: a toolkit for MD simulations of protein post-translational modifications [PDF]
Nucleic Acids Research, 2013 Post-translational modifications (PTMs) play a key role in numerous cellular processes by directly affecting structure, dynamics and interaction networks of target proteins. Despite their importance, our understanding of protein PTMs at the atomistic level is still largely incomplete.
Christian Margreitter +2 more
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PTM-Shepherd: analysis and summarization of post-translational and chemical modifications from open search results [PDF]
Molecular & Cellular Proteomics, 2020 ABSTRACT Open searching has proven to be an effective strategy for identifying both known and unknown modifications in shotgun proteomics experiments. Rather than being limited to a small set of user-specified modifications, open searches identify peptides with any mass shift that may correspond to a single modification or a combination
Daniel J. Geiszler +5 more
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Mechanisms of SOD1 regulation by post-translational modifications
Redox Biology, 2019 SOD1 is commonly known for its ROS scavenging activity, but recent work has uncovered additional roles in modulating metabolism, maintaining redox balance, and regulating transcription.
C.J. Banks, J.L. Andersen
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Advances on Post-translational Modifications Involved in Seed Germination
Frontiers in Plant Science, 2021 Seed germination and subsequent seedling establishment are important developmental processes that undergo extremely complex changes of physiological status and are precisely regulated at transcriptional and translational levels.
Feng Yu +3 more
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