Results 21 to 30 of about 43,191 (287)

RECENT ADVANCES IN POST-TRANSLATIONAL REGULATION OF PLANT DEFENSE RESPONSES BEYOND PHOSPHORYLATION [PDF]

open access: yesJournal of Plant Development, 2021
During plant-microbe interactions, plant immune signaling relies significantly on post-translational modifications (PTMs) to induce rapid downstream changes.
Tim XING, Ziwei GUO
doaj   +1 more source

Functional Regulation of Hsp70 Allostery by Post‐Translational Modifications (PTMs)

open access: yesThe FASEB Journal, 2020
The 70‐kDa heat shock proteins (Hsp70s) perform critical functions in the protein homeostasis network, such as assisting nascent chain folding, preventing protein misfolding and aggregation, facilitating assembly of complexes, and driving protein translocation.
Wenli Meng   +2 more
openaire   +1 more source

Post-Translational Modifications in Atopic Dermatitis: Current Research and Clinical Relevance

open access: yesFrontiers in Cell and Developmental Biology, 2022
Atopic dermatitis (AD) is a chronic and relapsing cutaneous disorder characterized by compromised immune system, excessive inflammation, and skin barrier disruption.
Xin Ma   +17 more
doaj   +1 more source

Identification of N-terminal protein acetylation and arginine methylation of the voltage-gated sodium channel in end-stage heart failure human heart [PDF]

open access: yes, 2014
The α subunit of the cardiac voltage-gated sodium channel, Naᵥ1.5, provides the rapid sodium inward current that initiates cardiomyocyte action potentials.
Batlle, Montserrat   +13 more
core   +2 more sources

Post-Translational Modification (PTM) Proteomics: Challenges and Perspectives [PDF]

open access: yesModern Chemistry & Applications, 2013
Copyright: © 2013 Darie CC. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
openaire   +1 more source

PTM-Shepherd: analysis and summarization of post-translational and chemical modifications from open search results [PDF]

open access: yesMolecular & Cellular Proteomics, 2020
ABSTRACTOpen searching has proven to be an effective strategy for identifying both known and unknown modifications in shotgun proteomics experiments. Rather than being limited to a small set of user-specified modifications, open searches identify peptides with any mass shift that may correspond to a single modification or a combination of several ...
Geiszler, Daniel J.   +5 more
openaire   +3 more sources

Investigation of post-translational modifications in type 2 diabetes

open access: yesClinical Proteomics, 2018
The investigation of post-translational modifications (PTMs) plays an important role for the study of type 2 diabetes. The importance of PTMs has been realized with the advancement of analytical techniques.
Bhaswati Chatterjee, Suman S. Thakur
doaj   +1 more source

An update on transcriptional and post-translational regulation of brain voltage-gated sodium channels [PDF]

open access: yes, 2015
Voltage-gated sodium channels are essential proteins in brain physiology, as they generate the sodium currents that initiate neuronal action potentials.
Beltran-Alvarez, Pedro   +1 more
core   +1 more source

Development and optimization of a miniaturized western blot-based screening platform to identify regulators of post-translational modifications [PDF]

open access: yes, 2019
Post-translational modifications (PTMs) are fundamental traits of protein functionality and their study has been addressed using several approaches over the past years.
Gottifredi, Vanesa   +2 more
core   +1 more source

Advances on Post-translational Modifications Involved in Seed Germination

open access: yesFrontiers in Plant Science, 2021
Seed germination and subsequent seedling establishment are important developmental processes that undergo extremely complex changes of physiological status and are precisely regulated at transcriptional and translational levels.
Feng Yu   +3 more
doaj   +1 more source

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