Results 41 to 50 of about 5,850,387 (280)

Proteome-wide profiling and mapping of post translational modifications in human hearts

open access: yesScientific Reports, 2021
Post translational modifications (PTMs) are covalent modifications of proteins that can range from small chemical modifications to addition of entire proteins.
Navratan Bagwan   +2 more
doaj   +1 more source

Advances on Post-translational Modifications Involved in Seed Germination

open access: yesFrontiers in Plant Science, 2021
Seed germination and subsequent seedling establishment are important developmental processes that undergo extremely complex changes of physiological status and are precisely regulated at transcriptional and translational levels.
Feng Yu   +3 more
doaj   +1 more source

Orchestrating the proteome with post-translational modifications [PDF]

open access: yes, 2018
Post-translational modifications (PTMs) add tremendous complexity to cellular proteomes. The large variety of these modifications and their concurrent appearance in proteins dramatically increase the proteome size from mere thousands to the order of ...
Spoel, Steven H.
core   +1 more source

The intricate dance of post-translational modifications in the rhythm of life. [PDF]

open access: yes, 2016
Endogenous biological rhythms with approximately 24-h periodicity are generated by the circadian clock, in which clock genes coordinate with one another and form a transcriptional-translational negative feedback loop. The precision of the circadian clock
Hirano, Arisa   +2 more
core   +1 more source

Evolutionary Signals in Coronaviral Structural Proteins Suggest Possible Complex Mechanisms of Post-Translational Regulation in SARS-CoV-2 Virus

open access: yesViruses, 2022
Post-translational regulation of proteins has emerged as a central topic of research in the field of functional proteomics. Post-translational modifications (PTMs) dynamically control the activities of proteins and are involved in a wide range of ...
Ramiro Garza-Domínguez   +1 more
doaj   +1 more source

Understanding and Exploiting Post-Translational Modifications for Plant Disease Resistance

open access: yes, 2021
Plants are constantly threatened by pathogens, so have evolved complex defence signalling networks to overcome pathogen attacks. Post-translational modifications (PTMs) are fundamental to plant immunity, allowing rapid and dynamic responses at the ...
Catherine Gough, Ari Sadanandom
core   +1 more source

Investigating Post-translational Modifications in Neuropsychiatric Disease: The Next Frontier in Human Post-mortem Brain Research

open access: yesFrontiers in Molecular Neuroscience, 2021
Gene expression and translation have been extensively studied in human post-mortem brain tissue from subjects with psychiatric disease. Post-translational modifications (PTMs) have received less attention despite their implication by unbiased genetic ...
Melanie J. Grubisha   +3 more
doaj   +1 more source

Networks of miRNAS with regular expression in patients with SLE and the associated proteins post-translational modifications (PTMs) coding genes.

open access: yes, 2019
Green sphere corresponds to the name of the associated proteins post-translational modifications (PTMs) and gray spheres are miRNAS. On the other hand, arrows show regulation by miRNAS to the mRNA of associated proteins post-translational modifications ...
Cecilia Fernández-Ponce (6876497)   +15 more
core   +1 more source

Post-Translational Modifications at the Coarse-Grained Level with the SIRAH Force Field

open access: yes, 2019
Post-translational modifications (PTMs) on proteins significantly enlarge the physicochemical diversity present in biological macromolecules, altering function, localization, and interactions. Despite their critical role in regulating cellular processes,
Pablo G. Garay (8250711)   +2 more
core   +6 more sources

Post-translational modifications involved in the biosynthesis of thiopeptide antibiotics

open access: yes, 2017
Thiopeptide antibiotics are generated from ribosomally synthesized peptides via a cascade of post-translational modifications (PTMs).
Qingfei Zheng, Hui Fang, Wen Liu
core   +1 more source

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