Antioxidant systems are regulated by nitric oxide-mediated post-translational modifications (NO-PTMs) [PDF]
Frontiers in Plant Science, 2016 Nitric oxide (NO) is a biological messenger that orchestrates a plethora of plant functions, mainly through post-translational modifications (PTMs) such as S-nitrosylation or tyrosine nitration.
Juan Carlos Begara-Morales +7 more
doaj +6 more sources
PTMs in Conversation: Activity and Function of Deubiquitinating Enzymes Regulated via Post-Translational Modifications [PDF]
Cell Biochemistry and Biophysics, 2011 Deubiquitinating enzymes (DUBs) constitute a diverse protein family and their impact on numerous biological and pathological processes has now been widely appreciated.
Benedikt M. Kessler, Mariola J. Edelmann
core +4 more sources
Protein post-translational modifications: In silico prediction tools and molecular modeling
Computational and Structural Biotechnology Journal, 2017 Post-translational modifications (PTMs) occur in almost all proteins and play an important role in numerous biological processes by significantly affecting proteins' structure and dynamics.
Martina Audagnotto, Matteo Dal Peraro
doaj +2 more sources
The Role of Protein Post-Translational Modifications in Fruit Ripening
HorticulturaeFruit ripening represents a multifaceted biological process intricately controlled by an array of plant hormones, transcription factors, and epigenetic modifications.
Ting Li +4 more
doaj +2 more sources
Post-Translational Modifications in Mammalian Folliculogenesis and Ovarian Pathologies
CellsPost-translational modifications (PTMs) of proteins, as the core mechanism for dynamically regulating follicular development, affect the maintenance of mammalian fertility by precisely coordinating granulosa cell–oocyte interaction, metabolic ...
Dake Chen +9 more
doaj +2 more sources
Role of non-canonical post-translational modifications in gastrointestinal tumors
Cancer Cell International, 2023 Post-translational modifications (PTMs) of proteins contribute to the occurrence and development of tumors. Previous studies have suggested that canonical PTMs such as ubiquitination, glycosylation, and phosphorylation are closely implicated in different
Yihong Liu +6 more
doaj +2 more sources
Roles of Post-translational Modifications in Spinocerebellar Ataxias [PDF]
Frontiers in Cellular Neuroscience, 2018 Post-translational modifications (PTMs), including phosphorylation, acetylation, ubiquitination, SUMOylation, etc., of proteins can modulate protein properties such as intracellular distribution, activity, stability, aggregation, and interactions ...
Linlin Wan +14 more
doaj +2 more sources
CellsAndrogen receptor (AR) transcriptional activity significantly influences prostate cancer (PCa) progression. In addition to ligand stimulation, AR transcriptional activity is also influenced by a variety of post-translational modifications (PTMs).
Lance Edward V. Lumahan +3 more
doaj +2 more sources
Role of Host-Mediated Post-Translational Modifications (PTMs) in RNA Virus Pathogenesis. [PDF]
Int J Mol Sci, 2020 Being opportunistic intracellular pathogens, viruses are dependent on the host for their replication. They hijack host cellular machinery for their replication and survival by targeting crucial cellular physiological pathways, including transcription, translation, immune pathways, and apoptosis.
Kumar R +4 more
europepmc +4 more sources
The Burden of Post-Translational Modification (PTM)—Disrupting Mutations in the Tumor Matrisome [PDF]
Cancers, 2021 Background: To evaluate the occurrence of mutations affecting post-translational modification (PTM) sites in matrisome genes across different tumor types, in light of their genomic and functional contexts and in comparison with the rest of the genome.
Elisa Holstein +7 more
openaire +3 more sources