Results 11 to 20 of about 469,548 (293)
Post‐Translational Modifications in Animal Circadian Clocks [PDF]
Advanced ScienceThe circadian clock is a fundamental biological system that synchronizes behavioral and physiological processes such as metabolism and immunity with the 24 h day‐night cycle.
Xianhui Liu, Yong Zhang
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Sirtuin Oxidative Post-translational Modifications [PDF]
Frontiers in Physiology, 2021 Increased sirtuin deacylase activity is correlated with increased lifespan and healthspan in eukaryotes. Conversely, decreased sirtuin deacylase activity is correlated with increased susceptibility to aging-related diseases.
Kelsey S. Kalous +2 more
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Post‐Translational Modifications in Cilia and Ciliopathies [PDF]
Advanced ScienceCilia are microtubule‐based organelles that extend from the surface of most vertebrate cells, and they play important roles in diverse cellular processes during embryonic development and tissue homeostasis.
Jie Ran, Jun Zhou
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Post-Translational Modifications and Diabetes
BiomoleculesDiabetes and its associated complications have increasingly become major challenges for global healthcare. The current therapeutic strategies involve insulin replacement therapy for type 1 diabetes (T1D) and small-molecule drugs for type 2 diabetes (T2D).
Chiranjeev Sharma +4 more
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Histone post-translational modifications of Leishmania braziliensis [PDF]
Scientific DataHistone post-translational modifications (hPTMs) constitute an epigenetic mechanism that plays a fundamental role in the regulation of gene expression in eukaryotic cells. In trypanosomatid parasites, such as Trypanosoma brucei, T.
Rafael Fogaça de Almeida +3 more
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Post-translational modifications of exosomal proteins
Frontiers in Immunology, 2014 Exosomes mediate intercellular communication and participate in many cell processes such as cancer progression, immune activation or evasion, and the spread of infection.
Olga eMoreno-Gonzalo +2 more
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Regulation of the microprocessor by post-translational modifications [PDF]
Frontiers in Cell and Developmental BiologyThe Microprocessor is an essential protein complex that is responsible for the first processing step in the biogenesis of canonical microRNAs. The core of this complex is composed of two proteins, the ribonuclease III enzyme DROSHA and its double ...
Ka Weng Leong +3 more
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Post-Translational Modifications of TRP Channels [PDF]
Cells, 2014 Transient receptor potential (TRP) channels constitute an ancient family of cation channels that have been found in many eukaryotic organisms from yeast to human.
Olaf Voolstra, Armin Huber
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Post-translational modifications of protein and lung cancer [PDF]
Frontiers in OncologyPost-translational modifications (PTMs) represent a pivotal regulatory mechanism in cellular processes, wherein the addition or removal of specific functional groups to amino acid residues dynamically modulates protein activity, subcellular localization,
Ying Zhao +10 more
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Post-translational modifications in prion diseases
Frontiers in Molecular NeuroscienceMore than 650 reversible and irreversible post-translational modifications (PTMs) of proteins have been listed so far. Canonical PTMs of proteins consist of the covalent addition of functional or chemical groups on target backbone amino-acids or the ...
Chloé Bizingre +12 more
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