Results 11 to 20 of about 314,987 (288)
Histone post-translational modifications of Leishmania braziliensis [PDF]
Scientific DataHistone post-translational modifications (hPTMs) constitute an epigenetic mechanism that plays a fundamental role in the regulation of gene expression in eukaryotic cells. In trypanosomatid parasites, such as Trypanosoma brucei, T.
Rafael Fogaça de Almeida +3 more
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Control of protein stability by post-translational modifications
Nature Communications, 2023 Here the authors summarize current knowledge of the regulation of protein stability by various post-translational modifications (PTMs) including methylation and phosphorylation.
Ji Min Lee +3 more
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Post-translational modifications of protein and lung cancer [PDF]
Frontiers in OncologyPost-translational modifications (PTMs) represent a pivotal regulatory mechanism in cellular processes, wherein the addition or removal of specific functional groups to amino acid residues dynamically modulates protein activity, subcellular localization,
Ying Zhao +10 more
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Post-translational modifications in prion diseases
Frontiers in Molecular NeuroscienceMore than 650 reversible and irreversible post-translational modifications (PTMs) of proteins have been listed so far. Canonical PTMs of proteins consist of the covalent addition of functional or chemical groups on target backbone amino-acids or the ...
Chloé Bizingre +12 more
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Post-translational modifications in heat stress-related diseases [PDF]
Frontiers in Molecular BiosciencesPost-translational modifications (PTMs) act as pivotal molecular hubs integrating heat stress signals into cellular responses driving heat-related diseases like heatstroke.
Qi Cui +4 more
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Surface Accessibility of Protein Post-Translational Modifications [PDF]
, 2007 Protein post-translational modifications are crucial to the function of many proteins. In this study, we have investigated the structural environment of 8378 incidences of 44 types of post-translational modifications with 19 different approaches. We show
Chi Nam Ignatius Pang (7446716) +2 more
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Sirtuin Oxidative Post-translational Modifications
Frontiers in Physiology, 2021 Increased sirtuin deacylase activity is correlated with increased lifespan and healthspan in eukaryotes. Conversely, decreased sirtuin deacylase activity is correlated with increased susceptibility to aging-related diseases.
Kelsey S. Kalous +2 more
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Post‐Translational Modifications of TOE3 Regulate Antiviral Defense in Tobacco [PDF]
Advanced SciencePost‐translational modifications (PTMs) affect the function of transcription factors and regulate plant immune responses. APETALA2 (AP2) transcription factor TARGET OF EAT3 (TOE3) plays a pivotal role in plant antiviral immunity. However, little is known
Bolei Jiao +3 more
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Post-translation modifications [PDF]
Current Opinion in Chemical Biology, 2009 The development of proteomics has been one of the great achievements in analytical chemical biology in the past ten years. The determination of the total protein constituents in biological samples has allowed new and unprecedented insights into cellular processes and diseases.
Carlito B, Lebrilla, Lara K, Mahal
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Post-translational modifications soften vimentin intermediate filaments [PDF]
, 2021 The mechanical properties of biological cells are determined by the cytoskeleton, a composite biopolymer network consisting of microtubules, actin filaments and intermediate filaments (IFs). By differential expression of cytoskeletal proteins, modulation
Denz, Manuela +17 more
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