Results 31 to 40 of about 5,990,239 (290)
Post-Translational Modifications of TRP Channels
Cells, 2014 Transient receptor potential (TRP) channels constitute an ancient family of cation channels that have been found in many eukaryotic organisms from yeast to human.
Olaf Voolstra, Armin Huber
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Proteomic interrogation of human chromatin. [PDF]
, 2011 Chromatin proteins provide a scaffold for DNA packaging and a basis for epigenetic regulation and genomic maintenance. Despite understanding its functional roles, mapping the chromatin proteome (i.e. the "Chromatome") is still a continuing process. Here,
LeRoy, Gary +30 more
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Post-translational protein modifications in schizophrenia [PDF]
npj Schizophrenia, 2020 AbstractResearch investigating the pathophysiology of schizophrenia has not yet precisely defined the molecular phenotype of this disorder. Many studies have investigated cellular dysfunction by examining expression levels of molecular targets in postmortem patient brain; however, inconsistencies between transcript and protein measures in schizophrenia
Toni M. Mueller +1 more
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Post-translational modifications of the polycystin proteins [PDF]
Cellular Signalling, 2020 Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney failure and affects up to 12 million people worldwide. Germline mutations in two genes, PKD1 or PKD2, account for almost all patients with ADPKD.
Streets, A., Ong, A.
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Oxidatively Modified Proteins: Cause and Control of Diseases
Applied Sciences, 2020 Proteins succumb to numerous post-translational modifications (PTMs). These relate to enzymatic or non-enzymatic reactions taking place in either the intracellular or extracellular compartment.
Ramona Clemen, Sander Bekeschus
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Post-translational modifications on the retinoblastoma protein
Journal of Biomedical Science, 2022 The retinoblastoma protein (pRb) functions as a cell cycle regulator controlling G1 to S phase transition and plays critical roles in tumour suppression. It is frequently inactivated in various tumours.
Linbin Zhou +6 more
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Potential protein post-translational modification in ERp57: A phenotype marker for male fertility
Journal of Human Reproductive Sciences, 2010 Background : In protein expression, post-translational modification is an important process. It is also an important process in human reproductive science. ERp57 is a molecule that is mentioned for post-translational modification. ERp57 is a component of
Viroj Wiwanitkit
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Scheme of EGR1 post-translational modifications.
, 2013 Scheme of EGR1 post-translational modifications.
Daniela Tavian (342557) +5 more
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Nature Communications, 2020 The mechanisms by which deubiquitinases modulate tumour progression are not fully understood. Here, the authors perform an RNAi screen and identify that the deubiquitinase OTUD5 suppresses cancer growth in a TRIM25 dependent manner, which in turn ...
Fangzhou Li +15 more
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Post-translational modifications soften vimentin intermediate filaments [PDF]
, 2021 The mechanical properties of biological cells are determined by the cytoskeleton, a composite biopolymer network consisting of microtubules, actin filaments and intermediate filaments (IFs). By differential expression of cytoskeletal proteins, modulation
Denz, Manuela +26 more
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