Results 1 to 10 of about 508,657 (349)

Post-translational processing of Schizosaccharomyces pombe YPT proteins.

open access: yesJournal of Biological Chemistry, 1992
ras proteins are post-translationally processed at their carboxyl-terminal CAAX motif by a triplet of modifications: prenylation of C with farnesyl, proteolytic trimming of AAX, and carboxyl-methylation. These modifications co-operate with palmitoylation
C. Newman   +5 more
semanticscholar   +3 more sources

Co- and post-translational processing of the hevein preproprotein of latex of the rubber tree (Hevea brasiliensis)

open access: yesJournal of Biological Chemistry, 1991
Hevein is a chitin-binding protein of 43 amino acids found in the lutoid body-enriched fraction of rubber tree latex. A hevein cDNA clone (HEV1) (Broekaert, W., Lee, H.-i., Kush, A., Nam, C.-H., and Raikhel, N. (1990) Proc. Natl. Acad. Sci. U.S.A.
Hyung-il Lee   +2 more
semanticscholar   +1 more source

The regulation of Hox gene expression during animal development [PDF]

open access: yes, 2013
Hox genes encode a family of transcriptional regulators that elicit distinct developmental programmes along the head-to-tail axis of animals. The specific regional functions of individual Hox genes largely reflect their restricted expression patterns ...
Alonso, Claudio R, Mallo, Moisés
core   +1 more source

Efficient trapping of HIV-1 envelope protein by hetero-oligomerization with an N-helix chimera

open access: yesRetrovirology, 2005
Background The N-heptad repeat region of the HIV-1 Transmembrane Envelope protein is a trimerization domain that forms part of a "six helix bundle" crucial to Envelope-mediated membrane fusion.
Silver Jonathan, Ou Wu
doaj   +1 more source

Recent advances in malaria genomics and epigenomics [PDF]

open access: yes, 2016
Malaria continues to impose a significant disease burden on low- and middle-income countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid sequencing, reverse genetics, and post-genome analyses has generated step ...
Kirchner, Sebastian   +2 more
core   +1 more source

Focal cerebral ischemia in rats alters APP processing and expression of Aβ peptide degrading enzymes in the thalamus

open access: yesNeurobiology of Disease, 2009
We have previously demonstrated aggregation of amyloid precursor protein (APP) and β-amyloid (Aβ) to dense plaque-like deposits in the thalamus of rats subjected to transient middle cerebral artery occlusion (MCAO).
Mikko Hiltunen   +6 more
doaj   +1 more source

Genome-scale modeling of the protein secretory machinery in yeast. [PDF]

open access: yesPLoS ONE, 2013
The protein secretory machinery in Eukarya is involved in post-translational modification (PTMs) and sorting of the secretory and many transmembrane proteins.
Amir Feizi   +4 more
doaj   +1 more source

Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders. [PDF]

open access: yes, 2016
Genes for autism spectrum disorders (ASDs) are also implicated in fragile X syndrome (FXS), intellectual disabilities (ID) or schizophrenia (SCZ), and converge on neuronal function and differentiation. The SH-SY5Y neuroblastoma cell line, the most widely
Chiocchetti, AG   +10 more
core   +1 more source

Dystrophin-Glycoprotein Complex: Post-translational Processing and Dystroglycan Function* 210

open access: yesJournal of Biological Chemistry, 2003
The dystrophin-glycoprotein complex (DGC) is a multimeric transmembrane protein complex first isolated from skeletal muscle membranes (1). The central protein of the DGC is dystroglycan (Fig. 1).
D. Michele, K. Campbell
semanticscholar   +1 more source

Gene induction during differentiation of human monocytes into dendritic cells: an integrated study at the RNA and protein levels [PDF]

open access: yes, 2001
Changes in gene expression occurring during differentiation of human monocytes into dendritic cells were studied at the RNA and protein levels. These studies showed the induction of several gene classes corresponding to various biological functions ...
Angénieux, C.   +9 more
core   +3 more sources

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