Cytoplasmic interaction with CYCLE promotes the post‐translational processing of the circadian CLOCK protein [PDF]
FEBS Letters, 2009 CLK (uniprotkb:O61735) binds (MI:0407) to Cyc (uniprotkb:O61734) by pull down (MI:0096)
Maurer, Christian +2 more
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Post-translational protein deimination signatures in sea lamprey (Petromyzon marinus) plasma and plasma-extracellular vesicles [PDF]
, 2021 Lampreys are a jawless vertebrate species belonging to an ancient vertebrate lineage that diverged from a common ancestor with humans ~500 million years ago.
Kraev, I +11 more
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Post-Translational Modifications of ATG4B in the Regulation of Autophagy
Cells, 2022 Autophagy plays a key role in eliminating and recycling cellular components in response to stress, including starvation. Dysregulation of autophagy is observed in various diseases, including neurodegenerative diseases, cancer, and diabetes.
Na Yeon Park, Doo Sin Jo, Dong-Hyung Cho
doaj +1 more source
SUMOylation by Pias1 regulates the activity of the Hedgehog dependent Gli transcription factors. [PDF]
PLoS ONE, 2010 BACKGROUND:Hedgehog (Hh) signaling, a vital signaling pathway for the development and homeostasis of vertebrate tissues, is mediated by members of the Gli family of zinc finger transcription factors. Hh signaling increases the transcriptional activity of
Barny Cox, James Briscoe, Fausto Ulloa
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Processing and targeting of proteins derived from polyprotein with 2A and LP4/2A as peptide linkers in a maize expression system. [PDF]
PLoS ONE, 2017 In the transformation of multiple genes, gene fusion is an attractive alternative to other methods, including sexual crossing, re-transformation, and co-transformation, among others.
He Sun +4 more
doaj +1 more source
Extensive post‐translational processing of potato tuber storage proteins and vacuolar targeting [PDF]
The FEBS Journal, 2011 Potato tuber storage proteins were obtained from vacuoles isolated from field‐grown starch potato tubers cv. Kuras. Vacuole sap proteins fractionated by gel filtration were studied by mass spectrometric analyses of trypsin and chymotrypsin digestions. The tuber vacuole appears to be a typical protein storage vacuole absent of proteolytic and glycolytic
Jørgensen, Malene +2 more
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Scientific Reports, 2021 Post-translational processing leads to conformational changes in protein structure that modulate molecular functions and change the signature of metabolic transformations and immune responses.
Dmitry Tikhonov +11 more
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The type II poly(A)-binding protein PABP-2 is a downstream target of the "let-7" microRNA in the heterochronic pathway of "Caenorhabditis elegans" : mechanisms of microRNA-mediated gene silencing in "Caenorhabditis elegans" [PDF]
, 2012 microRNAs (miRNAs) are a large class of small, non-coding RNAs that post-transcriptionally regulate gene expression in animals, plants and protozoa. miRNAs are genomically encoded and transcribed by RNA polymerase II. Primary transcripts are sequentially
Hurschler, Benjamin
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BMC Bioinformatics, 2022 Motivation Protein-protein interactions (PPIs) are critical to normal cellular function and are related to many disease pathways. A range of protein functions are mediated and regulated by protein interactions through post-translational modifications ...
Aparna Elangovan +4 more
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Peptidomics analysis of potato protein hydrolysates: post-translational modifications and peptide hydrophobicity [PDF]
, 2017 Post-translational modifications (PTMs) often occur in proteins and play a regulatory role in protein function. However, the role of PTMs in food-derived peptides remains largely unknown.
Shixiang Yao +3 more
core +1 more source