Results 11 to 20 of about 508,657 (349)

Post-translational processing targets functionally diverse proteins in Mycoplasma hyopneumoniae [PDF]

Open Biology, 2016
Mycoplasma hyopneumoniae is a genome-reduced, cell wall-less, bacterial pathogen with a predicted coding capacity of less than 700 proteins and is one of the smallest self-replicating pathogens. The cell surface of M.
Jessica L. Tacchi, Benjamin B. A. Raymond, Paul A. Haynes, Iain J. Berry, Michael Widjaja, Daniel R. Bogema, Lauren K. Woolley, Cheryl Jenkins, F. Chris Minion, Matthew P. Padula, Steven P. Djordjevic   +10 more
doaj   +5 more sources

Analysis of pmpD expression and PmpD post-translational processing during the life cycle of Chlamydia trachomatis serovars A, D, and L2. [PDF]

PLoS ONE, 2009
BACKGROUND: The polymorphic membrane protein D (PmpD) in Chlamydia is structurally similar to autotransporter proteins described in other bacteria and may be involved in cellular and humoral protective immunity against Chlamydia.
Andrey O Kiselev, Megan C Skinner, Mary F Lampe   +2 more
doaj   +2 more sources

Obesity Induces Hypothalamic Endoplasmic Reticulum Stress and Impairs Proopiomelanocortin (POMC) Post-translational Processing [PDF]

Journal of Biological Chemistry, 2013
It was shown previously that abnormal prohormone processing or inactive proconverting enzymes that are responsible for this processing cause profound obesity.
Cakir, Isin, Cyr, Nicole E., Litvinov, Bogdan Patedakis, Nillni, Eduardo A., Perello, Mario, Romero, Amparo, Stuart, Ronald C.   +6 more
core   +2 more sources

Cell specific post-translational processing of pikachurin, a protein involved in retinal synaptogenesis. [PDF]

PLoS ONE, 2012
Pikachurin is a recently identified, highly conserved, extracellular matrix-like protein. Murine pikachurin has 1,017 amino acids (~110 kDa), can bind to α-dystroglycan, and has been found to localize mainly in the synaptic cleft of photoreceptor ribbon ...
Jianzhong Han, Ellen Townes-Anderson
doaj   +4 more sources

Post-translational processing of the feline immunodeficiency virus envelope precursor protein.

Virology, 1993
The synthesis and processing of the envelope glycoprotein precursor of the feline immunodeficiency virus (FIV) isolate FIV-UT113 was investigated in a persistently infected Crandell feline kidney cell line (CRFK) and in an eukaryotic expression system ...
E. Verschoor, E. Hulskotte, J. Ederveen, M. Koolen, Marian C. Horzinek, P. Rottier   +5 more
semanticscholar   +4 more sources

Consequences of Disease-causing Mutations on Lubricin Protein Synthesis, Secretion, and Post-translational Processing* [PDF]

Journal of Biological Chemistry, 2005
Lubricin, a protein product of the gene PRG4, is a secreted mucin-like proteoglycan that is a major lubricant in articulating joints. Mutations in PRG4 cause the autosomal recessive, human disorder camptodactyly-arthropathy-coxa vara-pericarditis ...
David K. Rhee, J. Marcelino, S. Al‐Mayouf, Deborah K Schelling, C. Bartels, Yajun Cui, R. Laxer, R. Goldbach-Mansky, M. Warman   +8 more
semanticscholar   +3 more sources

Carboxyl-terminal Targeting and Novel Post-translational Processing of JAW1, a Lymphoid Protein of the Endoplasmic Reticulum* [PDF]

Journal of Biological Chemistry, 1996
Jaw1 is a lymphoid-restricted protein localized to the cytoplasmic face of the endoplasmic reticulum (ER) and is a member of a recently recognized class of integral membrane proteins that contain carboxyl-terminal membrane anchors.
T. Behrens, G. Kearns, J. J. Rivard, H. Bernstein, J. Yewdell, L. Staudt   +5 more
semanticscholar   +3 more sources

The post-translational processing of ras p21 is critical for its stimulation of mitogen-activated protein kinase.

Journal of Biological Chemistry, 1993
The point-mutated active form of ras p21 is known to activate mitogen-activated protein (MAP) kinase/extracellular signal-regulated kinase (ERK) in intact mammalian cells and Xenopus oocytes, although the direct target molecule of ras p21 remains to be ...
Takahito Itoh, K. Kaibuchi, T. Masuda, Toshiyoshi Yamamoto, Y. Matsuura, Akio Maeda, K. Shimizu, Y. Takai   +7 more
semanticscholar   +3 more sources

Modification of essential factors mediating post-translational processing for high-quality protein expression in Penicillium

Engineering Microbiology
The formation of mature proteins requires complex post-translational modification and processing. Efficient post-translational processing machinery is beneficial for the high-quality expression of proteins.
Demin Guo, Shengfang Zhao, Jie Chen, Shuhui Han, Yangtao Li, Yu Chen, Shengbiao Hu, Yibo Hu   +7 more
doaj   +2 more sources

Localization and Post-translational Processing of the Wound-induced Leucine Aminopeptidase Proteins of Tomato* [PDF]

Journal of Biological Chemistry, 1996
Leucine aminopeptidase (LAP) is induced by wounding and bacterial pathogen infection in tomato. DNA blot analysis of XbaI-digested λlap genomic clones demonstrated that LapA1 and LapA2 cDNAs were encoded by two different LapA genes in the tomato genome ...
Y. Gu, W. Chao, L. Walling
semanticscholar   +3 more sources