Results 21 to 30 of about 11,466,555 (302)

Large-scale protein-protein post-translational modification extraction with distant supervision and confidence calibrated BioBERT

BMC Bioinformatics, 2022
Motivation Protein-protein interactions (PPIs) are critical to normal cellular function and are related to many disease pathways. A range of protein functions are mediated and regulated by protein interactions through post-translational modifications ...
Aparna Elangovan, Yuan Li, Douglas E. V. Pires, Melissa J. Davis, Karin Verspoor   +4 more
doaj   +1 more source

Proteomic and molecular dynamic investigations of PTM-induced structural fluctuations in breast and ovarian cancer

Scientific Reports, 2021
Post-translational processing leads to conformational changes in protein structure that modulate molecular functions and change the signature of metabolic transformations and immune responses.
Dmitry Tikhonov, Liudmila Kulikova, Arthur T. Kopylov, Vladimir Rudnev, Alexander Stepanov, Kristina Malsagova, Alexander Izotov, Dmitry Kulikov, Alexey Zulkarnaev, Dmitry Enikeev, Natalia Potoldykova, Anna L. Kaysheva   +11 more
doaj   +1 more source

Post-Translational Membrane Protein Targeting by the Chloroplast Signal Recognition Particle [PDF]

, 2011
Post-translational transport of membrane proteins poses enormous challenges to the cells. The transport factors must accurately select and deliver the cargos to the appropriate target membranes.
Jaru-Ampornpan, Peera
core   +1 more source

Effects of post-translational modifications on prion protein aggregation and the propagation of scrapie-like characteristics in vitro [PDF]

, 2007
Prion diseases, or transmissible spongiform encephalopathies (TSEs) are typically characterised by CNS accumulation of PrPSc, an aberrant conformer of a normal cellular protein PrPC.
Oxley, David, Meersman, Filip, Webster, Judith, Kazlauskaite, Jurate, Pinheiro, Teresa J. T., Young, Duncan S., Dear, Denise V., Lowe, Christopher R., Gill, Andrew C., Bronstein, Igor   +9 more
core   +1 more source

Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I [PDF]

, 2010
Mammalian cleavage factor I (CF Im) is composed of two polypeptides of 25 kDa and either a 59 or 68 kDa subunit (CF Im25, CF Im59, CF Im68). It is part of the cleavage and polyadenylation complex responsible for processing the 39 ends of messenger RNA ...
Antje Ostareck-Lederer, Neuenkirchen, N., Ostareck-Lederer, Antje, Keller, W., Dettwiler, Sabine, Sabine Dettwiler, Fischer, Utz, Martin, Georges, Rüegsegger, U., Fischer, U., Georges Martin, Ashwin Chari, Blank, Diana, Diana Blank, Neuenkirchen, Nils, Blank, D., Utz Fischer, Chari, Ashwin, Ostareck-Lederer, A., Nils Neuenkirchen, Walter Keller, Chari, A., Ursula Rüegsegger, Dettwiler, S., Martin, G., Keller, Walter, Rüegsegger, Ursula, Rüegsegger U, Martin G, Chari A, Neuenkirchen N, Fischer U, Keller W, Blank D, Dettwiler S, Ostareck-Lederer A   +35 more
core   +1 more source

Extracellular Vesicles and Post-translational Protein Deimination Signatures in Haemolymph of the American Lobster (Homarus americanus) [PDF]

, 2020
The American lobster (Homarus americanus) is a commercially important crustacean with an unusual long life span up to 100 years and a comparative animal model of longevity.
Lange, S., Kraev, Igor, Igor Kraev, Bowden, Timothy J., Lange, Sigrun, Sigrun Lange, Timothy J. Bowden, Bowden, T.J., Kraev, I.   +8 more
core   +1 more source

Post-translational Processing of the Feline Immunodeficiency Virus Envelope Precursor Protein

Virology, 1993
The synthesis and processing of the envelope glycoprotein precursor of the feline immunodeficiency virus (FIV) isolate FIV-UT113 was investigated in a persistently infected Crandell feline kidney cell line (CRFK) and in an eukaryotic expression system.
Horzinek, M.C., Verschoor, E.J., Hulskotte, E.G., Ederveen, J., Koolen, M.J.M., Rottier, P.J.M.   +5 more
openaire   +3 more sources

Primary structure and post-translational processing of the berne virus peplomer protein

Virology, 1990
The nucleotide sequence of the peplomer (P) protein gene of Berne virus (BEV), the torovirus prototype, was determined. The gene encodes an apoprotein of 1581 amino acids with an Mr of about 178K. The open reading frame was cloned behind the T7 RNA polymerase promoter and its translation product was identified as the BEV P protein precursor by in vivo ...
Snijder, Eric J, Den Boon, Johan A, Spaan, Willy J.M, Weiss, Marianne, Horzinek, Marian C   +4 more
openaire   +3 more sources

Peptidomics analysis of potato protein hydrolysates: post-translational modifications and peptide hydrophobicity [PDF]

, 2017
Post-translational modifications (PTMs) often occur in proteins and play a regulatory role in protein function. However, the role of PTMs in food-derived peptides remains largely unknown.
Shixiang Yao, Chibuike, Udenigwe, Chibuike Udenigwe, Shixiang, Yao   +3 more
core   +2 more sources

Post-translational processing of Schizosaccharomyces pombe YPT proteins.

Journal of Biological Chemistry, 1992
ras proteins are post-translationally processed at their carboxyl-terminal CAAX motif by a triplet of modifications: prenylation of C with farnesyl, proteolytic trimming of AAX, and carboxyl-methylation. These modifications co-operate with palmitoylation of nearby sites or a polybasic region to target plasma membrane localization.
C M, Newman, T, Giannakouros, J F, Hancock, E H, Fawell, J, Armstrong, A I, Magee   +5 more
openaire   +2 more sources