Results 21 to 30 of about 508,657 (349)
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2010 Work is presented on the role of cAMP-dependent protein phosphorylation in post-translational processing and biosynthesis of complex I subunits in mammalian cell cultures. PKA-mediated phosphorylation of the NDUFS4 subunit of complex I promotes in cell cultures in vivo import/maturation in mitochondria of the precursor of this protein.
S. Papa +11 more
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The Role of Pumilio RNA Binding Protein in Plants
Biomolecules, 2021 Eukaryotic organisms have a posttranscriptional/translational regulation system for the control of translational efficiency. RNA binding proteins (RBPs) have been known to control target genes.
Sung Un Huh
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Frontiers in Physiology, 2021 The accumulation of unfolded/misfolded proteins in the endoplasmic reticulum (ER) causes ER stress and induces the unfolded protein response (UPR) and other mechanisms to restore ER homeostasis, including translational shutdown, increased targeting of ...
Emily M. Nakada +7 more
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Journal of Experimental & Clinical Cancer Research, 2021 Background Murine xenografts of pediatric leukemia accurately recapitulate genomic aberrations. How this translates to the functional capacity of cells remains unclear. Here, we studied global protein abundance, phosphorylation, and protein maturation by
Anuli C. Uzozie +11 more
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Coordination of RNA Processing Regulation by Signal Transduction Pathways
Biomolecules, 2021 Signal transduction pathways transmit the information received from external and internal cues and generate a response that allows the cell to adapt to changes in the surrounding environment.
Veronica Ruta +2 more
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Proteomes, 2022 Biological activity regulation by protein post-translational modification (PTM) is critical for cell function, development, differentiation, and survival.
Amir Taldaev +6 more
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Post-translational protein modifications in schizophrenia
npj Schizophrenia, 2020 Research investigating the pathophysiology of schizophrenia has not yet precisely defined the molecular phenotype of this disorder. Many studies have investigated cellular dysfunction by examining expression levels of molecular targets in postmortem ...
T. Mueller, J. Meador-Woodruff
semanticscholar +1 more source
Frontiers in Molecular Biosciences, 2021 Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP family of conserved proteins that is involved in RNA transcription, pre-mRNA splicing, mRNA transport, protein translation, microRNA processing, telomere maintenance and the ...
Joseph P. Clarke +9 more
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Extensive post‐translational processing of potato tuber storage proteins and vacuolar targeting [PDF]
The FEBS Journal, 2011 Potato tuber storage proteins were obtained from vacuoles isolated from field‐grown starch potato tubers cv. Kuras. Vacuole sap proteins fractionated by gel filtration were studied by mass spectrometric analyses of trypsin and chymotrypsin digestions. The tuber vacuole appears to be a typical protein storage vacuole absent of proteolytic and glycolytic
Jørgensen, Malene +2 more
openaire +4 more sources
Post-Translational Modifications of ATG4B in the Regulation of Autophagy
Cells, 2022 Autophagy plays a key role in eliminating and recycling cellular components in response to stress, including starvation. Dysregulation of autophagy is observed in various diseases, including neurodegenerative diseases, cancer, and diabetes.
Na Yeon Park, Doo Sin Jo, Dong-Hyung Cho
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