Results 21 to 30 of about 5,990,239 (290)
Post-translational modifications of microtubules [PDF]
Journal of Cell Science, 2010 Microtubules – polymers of tubulin – perform essential functions, including regulation of cell shape, intracellular transport and cell motility. How microtubules are adapted to perform multiple diverse functions is not well understood. Post-translational modifications of tubulin subunits diversify the outer and luminal surfaces of microtubules and ...
Dorota, Wloga, Jacek, Gaertig
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Post-translational modifications of tubulin [PDF]
Current Biology, 2014 Microtubules are the largest filamentous components of the eukaryotic cytoskeleton. In spite of their extraordinary level of structural conservation, microtubules fulfill a vast range of different functions in cells. How this functional diversity is achieved remains an open question; however, recent advances point towards post-translational ...
Magiera, Maria M., Janke, Carsten
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Post-translational modification by SUMO [PDF]
Toxicology, 2010 Post-translational modifications (PTMs) are chemical alterations to a protein following translation, regulating stability and function. Reversible phosphorylation is an example of an important and well studied PTM involved in a number of cellular processes.
Hannoun, Zara +4 more
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Mass Spectrometry to Identify Post-Translational Modifications.
, 2008 The analysis of post-translational modifications using mass spectrometric-based strategies is a rapidly growing area of post-genome science. This chapter describes an overview of the techniques currently used in the analysis of some of the more common ...
Gaskell, S, Eyers, C
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Post translational modification of Parkin [PDF]
Biology Direct, 2017 Mutations in the gene encoding for the E3 ubiquitin ligase Parkin are associated to a rare form of familiar autosomal recessive Parkinsonism. Despite decades of research on the Parkin protein, whose structure has been recently solved, little is known about the specific signalling pathways that lead to Parkin activation.
Chakraborty, Joy +2 more
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Surface Accessibility of Protein Post-Translational Modifications
, 2007 Protein post-translational modifications are crucial to the function of many proteins. In this study, we have investigated the structural environment of 8378 incidences of 44 types of post-translational modifications with 19 different approaches. We show
Chi Nam Ignatius Pang (7446716) +2 more
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Deciphering post‐translational modification codes [PDF]
FEBS Letters, 2013 Post‐translational modifications (PTMs) occur on nearly all proteins. Many domains within proteins are modified on multiple amino acid sidechains by diverse enzymes to create a myriad of possible protein species. How these combinations of PTMs lead to distinct biological outcomes is only beginning to be understood.
Lothrop, Adam P. +2 more
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Post‐translation modification of proteins in tears [PDF]
ELECTROPHORESIS, 2010 AbstractThis is the first 2‐DE study using sequential dyes to analyse phospho‐, glyco‐ and total tear protein profiles (Pro‐Q Diamond for phosphoprotein, Pro‐Q Emerald for glycoprotein and Sypro Ruby for total protein). This method minimised the gel–gel variations, allowing better comparisons among the three profiles and generated a whole map of PTM ...
You, Jingjing +10 more
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Post Translational Modifications of Eukaryotic Initiation Factor 2A [PDF]
, 2008 Post translational modifications of eukaryotic initiation factor 2A under ...
Bick, Gregory +2 more
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Post-translational modifications of transporters
Pharmacology & Therapeutics, 2018 Drug transporter proteins are critical to the distribution of a wide range of endogenous compounds and xenobiotics such as hormones, bile acids, peptides, lipids, sugars, and drugs. There are two classes of drug transporters- the solute carrier (SLC) transporters and ATP-binding cassette (ABC) transporters -which predominantly differ in the energy ...
Lindsay C, Czuba +2 more
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