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Post-translational modifications in heat stress-related diseases [PDF]
Frontiers in Molecular BiosciencesPost-translational modifications (PTMs) act as pivotal molecular hubs integrating heat stress signals into cellular responses driving heat-related diseases like heatstroke.
Qi Cui +4 more
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Post‐Translational Modifications of TOE3 Regulate Antiviral Defense in Tobacco [PDF]
Advanced SciencePost‐translational modifications (PTMs) affect the function of transcription factors and regulate plant immune responses. APETALA2 (AP2) transcription factor TARGET OF EAT3 (TOE3) plays a pivotal role in plant antiviral immunity. However, little is known
Bolei Jiao +3 more
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Absolute quantitation of post-translational modifications [PDF]
Frontiers in Chemistry, 2014 The cell's fate is largely governed by the dynamics of cellular events, brought about by the interplay of various proteins, in which post-translational modifications (PTMs) play a key role. Therefore, a better understanding of post-translational modification is of utmost importance to a biochemist.
Ruchi eChaube
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Post-translation modifications [PDF]
Current Opinion in Chemical Biology, 2009 The development of proteomics has been one of the great achievements in analytical chemical biology in the past ten years. The determination of the total protein constituents in biological samples has allowed new and unprecedented insights into cellular processes and diseases.
Carlito B, Lebrilla, Lara K, Mahal
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Deciphering post‐translational modification codes [PDF]
FEBS Letters, 2013 Post‐translational modifications (PTMs) occur on nearly all proteins. Many domains within proteins are modified on multiple amino acid sidechains by diverse enzymes to create a myriad of possible protein species. How these combinations of PTMs lead to distinct biological outcomes is only beginning to be understood.
Lothrop, Adam P. +2 more
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Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications [PDF]
, 2012 Conjugation of ubiquitin to proteins (ubiquitylation) has emerged to be one of the most crucial post-translational modifications controlling virtually all cellular processes.
Fulda, Simone +2 more
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Post-Translational Modifications That Drive Prostate Cancer Progression
Biomolecules, 2021 While a protein primary structure is determined by genetic code, its specific functional form is mostly achieved in a dynamic interplay that includes actions of many enzymes involved in post-translational modifications.
Ivana Samaržija
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Post-Translational Modifications of Extracellular Proteasome
Molecules, 2020 The ubiquitin-proteasome system (UPS) is one of the major protein degradation pathways in eukaryotic cells. Abnormal functioning of this system has been observed in cancer and neurological diseases.
Anna S. Tsimokha +4 more
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“NO” Time in Fear Response: Possible Implication of Nitric-Oxide-Related Mechanisms in PTSD
Molecules, 2023 Post-traumatic stress disorder (PTSD) is a psychiatric condition characterized by persistent fear responses and altered neurotransmitter functioning due to traumatic experiences.
Mariana G. Fronza +4 more
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Post-Translational Modifications Aid Archaeal Survival
Biomolecules, 2020 Since the pioneering work of Carl Woese, Archaea have fascinated biologists of almost all areas given their unique evolutionary status, wide distribution, high diversity, and ability to grow in special environments.
Ping Gong +4 more
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