Results 141 to 150 of about 4,630,754 (316)
Similarities between sweet protein thaumatin and a pathogenisis-related protein from tobacco
A pathogenesis-related protein, PR-R from virus-infected tobacco leaves, has been compared in immunological, electrophoretic and chromatographic properties with the sweet protein thaumatin with which it is believed to have ∼ 65% homology of amino acid ...
William S. Pierpoint +3 more
core +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Protein S in cancer patients with non-metastatic solid tumors
AIMS: To study protein S, as an acute phase protein, for its relationships with C4b-BP (C4BP), fibrinogen and Factor VIII:C in a group of patients with solid tumours, without proven metastases.
Vittoria A. +4 more
core +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Protein-protein interactions underlying damage checkpoint activation in S. pombe
DNA damage can lead to the accumulation of mutations and diseases such as cancer. It is therefore integral for cells to identify this damaged DNA and promote its repair.
Christopher Wardlaw (16180916)
core
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Protein structural modifications induced by physical processing [PDF]
This contribution focuses on the molecular determinants and the biotechnologically relevant consequences of structural modification of protein ensuing from: 1) physical treatments that alter the structure of solvent water (such as temperature of high ...
S. Iametti
core
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Domain discovery method for topological profile searches in protein structures
We describe a method for automated domain discovery for topological profile searches in protein structures. The method is used in a system TOPStructure for fast prediction of CATH classification for protein structures (given as PDB files).
Viksna, J +5 more
core

