Results 261 to 270 of about 6,974,231 (359)

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

Advanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni, Kuoran Xing, Bihan Zhang, Baoteng Wang, Yinglu Chen, Jianping Xie, Xiao Sun, Jinping Wang, David Tai Leong   +8 more
wiley   +1 more source

A yeast surface display platform for screening of non-enzymatic protein secretion in Kluyveromyces lactis. [PDF]

Appl Microbiol Biotechnol
An J, Shang N, Liu W, Niu Y, Liang Q, Jiang J, Zheng Y.   +6 more
europepmc   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure. [PDF]

Commun Biol
Katsuura M, Homma J, Higashi Y, Sekine H, Shimizu T.   +4 more
europepmc   +1 more source

4D‐Printable Poly(Thio)urethane Photoresins With Reactive Oxygen Species Responsiveness and Anti‐Inflammatory Functionality

Advanced Functional Materials, EarlyView.
This work introduces UV‐curable poly(thio)urethane (PSU) thermosets as 4D printable scaffolds responsive to oxidative stress. PSU networks with 100 wt.% polypropylene glycol (PPG) effectively suppress inflammatory markers in microglial cells to basal values.
Xabier Lopez de Pariza, Lolita Arévalo‐Lagos, Louise Breloy, Oihane Varela, Aitor Larrañaga, Juan F. Cadavid‐Vargas, Olaia Garagarza‐Goienetxea, Melissa Moya‐Granados, Vanessa Bagnarello, Haritz Sardon, Miryam Criado‐Gonzalez   +10 more
wiley   +1 more source

Author Correction: Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure. [PDF]

Commun Biol
Katsuura M, Homma J, Higashi Y, Sekine H, Shimizu T.   +4 more
europepmc   +1 more source

MOESM6 of Effect of secretory pathway gene overexpression on secretion of a fluorescent reporter protein in Aspergillus nidulans

, 2016
Martin Schalén, Diana Chinyere Anyaogu, Jakob Blæsbjerg Hoof, Mhairi Workman   +3 more
openalex   +1 more source

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak, Marcell Papp, Carolina Paganini, Andrea Zendrini, Paolo Bergese, Dorothea Pinotsi, Paolo Arosio   +6 more
wiley   +1 more source

Protein secretion routes in fungi are mostly determined by the length of the hydrophobic helix in the signal peptide

Sones-Dykes T, Wallace E.
europepmc   +1 more source

Mechanism of type‐III protein secretion: Regulation of FlhA conformation by a functionally critical charged‐residue cluster

, 2017
Marc Erhardt, Paige Wheatley, Eun A Kim, Takanori Hirano, Yang Zhang, Mayukh K. Sarkar, Kelly T. Hughes, David F. Blair   +7 more
openalex   +1 more source