Results 151 to 160 of about 209,848 (307)
Emergence of Catalytic Activity in VRK3: Phosphoproteomic Insights into the Regulatory Network of a Former Pseudokinase. [PDF]
ProteomesSujina A +4 more
europepmc +1 more source
International Journal of Cancer, EarlyView.What's New? Colorectal cancer (CRC) is increasingly complicated by drug‐resistant tumors that limit the effectiveness of anticancer therapies. Because resistance mechanisms vary among patients and can evolve over time, personalized treatment strategies are needed.
Keren Zohar +16 more
wiley +1 more source
PHGDH phosphorylation mediated by WNK1 serves as a dual marker of metabolic vulnerability and responsiveness to oxaliplatin treatment. [PDF]
Proc Natl Acad Sci U S AFang S +15 more
europepmc +1 more source
Second‐trimester multimetabolite panel for early preeclampsia rule‐out
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective We aimed to establish a high‐sensitivity, multimetabolite rule‐out model for the development of preeclampsia (PE), prioritizing minimizing false negatives to exclude low‐risk individuals from intensive surveillance confidently. Methods In this prospective, nested case–control study, maternal serum samples were collected between 20+0 ...
Matthews Silva Martins +7 more
wiley +1 more source
Decoding Cdk1 control: from mitotic thresholds to meiotic specificity. [PDF]
Chromosome ResTouati SA.
europepmc +1 more source
iNew Medicine, EarlyView.ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little +12 more
wiley +1 more source