Results 11 to 20 of about 220,067 (314)
Extensive feature detection of N-terminal protein sorting signals [PDF]
Bioinformatics, 2002 Abstract Motivation: The prediction of localization sites of various proteins is an important and challenging problem in the field of molecular biology. TargetP, by Emanuelsson et al. (J. Mol. Biol. , 300, 1005–1016, 2000) is a neural network based system which is currently the best predictor in the literature for N-terminalsorting ...
Hideo, Bannai +4 more
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Response: The Mitochondrial β-Signal and Protein Sorting [PDF]
Cell, 2008 The outer membranes of mitochondria, chloroplasts, and Gram-negative bacteria contain abundant β-barrel proteins that are essential for the transport of proteins and metabolites. Identification of the mitochondrial sorting and assembly machinery (SAM complex) revealed a new protein import pathway and sparked interest in mitochondrial β-barrel ...
Kutik, Stephan +12 more
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JCI Insight, 2023 Glioblastoma is the most malignant primary brain tumor, the prognosis of which remains dismal even with aggressive surgical, medical, and radiation therapies. Glioblastoma stem cells (GSCs) promote therapeutic resistance and cellular heterogeneity due to their self-renewal properties and capacity for plasticity.
Ryan C. Gimple +19 more
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Biotechnology for Biofuels and Bioproducts, 2022 Background The budding yeast Komagataella phaffii (Pichia pastoris) is widely employed to secrete proteins of academic and industrial interest.
Chenwei Zou +6 more
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Sorting pathways of mitochondrial inner membrane proteins [PDF]
, 1990 Two distinct pathways of sorting and assembly of nuclear-encoded mitochondrial inner membrane proteins are described. In the first pathway, precursor proteins that carry amino-terminal targeting signals are initially translocated via contact sites ...
Hartl, Franz-Ulrich +5 more
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Intra-ER sorting of the peroxisomal membrane protein Pex3 relies on its luminal domain
Biology Open, 2013 Summary Pex3 is an evolutionarily conserved type III peroxisomal membrane protein required for peroxisome formation. It is inserted into the ER membrane and sorted via an ER subdomain (the peroxisomal ER, or pER) to peroxisomes.
Mohammad H. Fakieh +5 more
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Delivering of Proteins to the Plant Vacuole-An Update [PDF]
, 2014 Trafficking of soluble cargo to the vacuole is far from being a closed issue as it can occur by different routes and involve different intermediates.
Claudia Pereira +2 more
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Machine learning approaches for the prediction of signal peptides and other protein sorting signals [PDF]
Protein Engineering, Design and Selection, 1999 Prediction of protein sorting signals from the sequence of amino acids has great importance in the field of proteomics today. Recently, the growth of protein databases, combined with machine learning approaches, such as neural networks and hidden Markov models, have made it possible to achieve a level of reliability where practical use in, for example ...
H, Nielsen, S, Brunak, G, von Heijne
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The c-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuole [PDF]
, 2003 We have assessed the ability of the plant secretory pathway to handle the expression of complex heterologous proteins by investigating the fate of a hybrid immunoglobulin A/G in tobacco cells.
Hadlington, Jane L. +6 more
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PLoS ONE, 2014 Trafficking of integral membrane proteins between the ER and Golgi complex, and protein sorting and trafficking between the TGN and endosomal/lysosomal compartments or plasma membranes, are dependent on cis-acting, linear amino acid sorting signals ...
Hirendrasinh B Parmar +2 more
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