Results 31 to 40 of about 220,067 (314)

Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis [PDF]

Journal of Clinical Investigation, 2016
Certain secretory proteins are known to be critical for maintaining the stemness of stem cells through autocrine signaling. However, the processes underlying the biogenesis, maturation, and secretion of these proteins remain largely unknown. Here we demonstrate that many secretory proteins produced by hematopoietic stem cells (HSCs) undergo exosomal ...
Hao, Gu, Chiqi, Chen, Xiaoxin, Hao, Conghui, Wang, Xiaocui, Zhang, Zhen, Li, Hongfang, Shao, Hongxiang, Zeng, Zhuo, Yu, Li, Xie, Fangzhen, Xia, Feifei, Zhang, Xiaoye, Liu, Yaping, Zhang, Haishan, Jiang, Jun, Zhu, Jiangbo, Wan, Chun, Wang, Wei, Weng, Jingjing, Xie, Minfang, Tao, Cheng Cheng, Zhang, Junling, Liu, Guo-Qiang, Chen, Junke, Zheng   +24 more
openaire   +2 more sources

TRAM is involved in IL-18 signaling and functions as a sorting adaptor for MyD88. [PDF]

PLoS ONE, 2012
MyD88, a Toll/interleukin-1 receptor homology (TIR) domain-containing adaptor protein, mediates signals from the Toll-like receptors (TLR) or IL-1/IL-18 receptors to downstream kinases. In MyD88-dependent TLR4 signaling, the function of MyD88 is enhanced
Hidenori Ohnishi, Hidehito Tochio, Zenichiro Kato, Norio Kawamoto, Takeshi Kimura, Kazuo Kubota, Takahiro Yamamoto, Tatsuyoshi Funasaka, Hiroshi Nakano, Richard W Wong, Masahiro Shirakawa, Naomi Kondo   +11 more
doaj   +1 more source

Production of the main celiac disease autoantigen by transient expression in Nicotiana benthamiana [PDF]

, 2015
Celiac Disease (CD) is a gluten sensitive enteropathy that remains widely undiagnosed and implementation of massive screening tests is needed to reduce the long term complications associated to untreated CD.
Acevedo, Gonzalo Raúl, Bayardo, Mariela Paula, Chirdo, Fernando Gabriel, Marin Viegas, Vanesa Soledad, Petruccelli, Silvana   +4 more
core   +2 more sources

Multiple Sorting Signals Determine Apical Localization of a Nonglycosylated Integral Membrane Protein [PDF]

Journal of Biological Chemistry, 1997
In polarized cells, newly synthesized proteins are sorted in the trans-Golgi network and from there delivered to either the apical or basolateral membranes. Madin-Darby canine kidney (MDCK) cells have been widely used as a model system to study sorting determinants to the apical and basolateral surfaces.
M A, Alonso, L, Fan, B, Alarcón
openaire   +2 more sources

Distinct pathways mediate the sorting of tail-anchored proteins to the plastid outer envelope. [PDF]

PLoS ONE, 2010
Tail-anchored (TA) proteins are a distinct class of membrane proteins that are sorted post-translationally to various organelles and function in a number of important cellular processes, including redox reactions, vesicular trafficking and protein ...
Preetinder K Dhanoa, Lynn G L Richardson, Matthew D Smith, Satinder K Gidda, Matthew P A Henderson, David W Andrews, Robert T Mullen   +6 more
doaj   +1 more source

Anchoring of proteins to lactic acid bacteria [PDF]

, 1999
The anchoring of proteins to the cell surface of lactic acid bacteria (LAB) using genetic techniques is an exciting and emerging research area that holds great promise for a wide variety of biotechnological applications. This paper reviews five different
A Hoick, A Mercenier, A Robert, A Strauss, A Strauss, AJ Haandrikman, AP Pugsley, C Andréoni, CBM Maassen, CM Franke, CM Franke, CM Rush, D Medaglini, D Medaglini, D Medaglini, E Gunneriusson, FO Eko, G Buist, G Buist, G Georgiou, G Pozzi, G Pozzi, G Pozzi, G Pozzi, G Pozzi, G Vidgrén, H Ton-That, H Ton-That, HJ Boot, I Poquet, J Kok, JC Piard, JM Wells, K Robinson, L Steidler, M, M Hansson, M Hofnung, ML Callegari, MR Oggioni, MR Oggioni, O Schneewind, O Schneewind, O Schneewind, P Samuelson, P Vos, PH Pouwels, PH Pouwels, PM Norton, PM Norton, RJ Leer, S Fabio, S Liljeqvist, S Ricci, S Stahl, S Tynkkynen, SC Cebolla, T Toba, TN Nguyen, TN Nguyen, UB Sleytr, VA Fischetti, VA Fischetti, VA Fischetti, WW Navarre, WW Navarre, WW Navarre   +66 more
core   +1 more source

An N‐terminal hydrophobic peak is the sorting signal of regulated secretory proteins [PDF]

FEBS Letters, 1995
Endocrine and exocrine cells each contain a regulated and constitutive secretory pathway. The presence of two distinct secretory pathways in the same cell type requires a sorting step to direct secretory proteins to the correct pathway. It is thought that regulated secretory proteins contain a specific sorting signal.
Gorr, Sven-Ulrik, Darling, Douglas S.
openaire   +2 more sources

The C-terminus of Bienertia sinuspersici Toc159 contains essential elements for its targeting and anchorage to the chloroplast outer membrane

Frontiers in Plant Science, 2014
Most nucleus-encoded chloroplast proteins rely on an N-terminal transit peptide (TP) as a post-translational sorting signal for directing them to the organelle.
Shiu-Cheung eLung, Matthew D Smith, Kyle eWeston, William eGwynne, Nathan eSecord, Simon Dich Xung Chuong   +5 more
doaj   +1 more source

Membrane-associated proteins in giardia lamblia [PDF]

, 2018
The manner in which membrane-associated proteins interact with the membrane defines their subcellular fate and function. This interaction relies on the characteristics of the proteins, their journey after synthesis, and their interaction with other ...
Feliziani, Constanza, Ropolo, Andrea Silvana, Touz, Maria Carolina   +2 more
core   +1 more source

Construction of a weight-based seed sorting system for the third-generation hybrid rice

Rice, 2021
Background The third-generation hybrid rice technology can be constructed by transforming a recessive nuclear male sterile (NMS) mutant with a transgenic cassette containing three functional modules: the wild type male fertility gene to restore the ...
Jianxin Wu, Shijun Qiu, Menglong Wang, Chunjue Xu, Xing Wang Deng, Xiaoyan Tang   +5 more
doaj   +1 more source