Results 11 to 20 of about 4,545,906 (256)
Signals involved in protein intracellular sorting [PDF]
, 2005 “…Confusion appears to occur just after the articulation of a major conceptual advance that served to greatly clarify a problem of exceptional importance.”- Ira Mellman, 1996. What could be more fitting than the domain of protein trafficking to elucidate the above statement made by one of the several pioneers in the field? Ever since the pioneering
Nair, Prashant
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Response: The Mitochondrial β-Signal and Protein Sorting [PDF]
Cell, 2008 The outer membranes of mitochondria, chloroplasts, and Gram-negative bacteria contain abundant β-barrel proteins that are essential for the transport of proteins and metabolites. Identification of the mitochondrial sorting and assembly machinery (SAM complex) revealed a new protein import pathway and sparked interest in mitochondrial β-barrel ...
Kutik, Stephan +12 more
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Machine learning approaches for the prediction of signal peptides and other protein sorting signals [PDF]
Protein Engineering, Design and Selection, 1999 Prediction of protein sorting signals from the sequence of amino acids has great importance in the field of proteomics today. Recently, the growth of protein databases, combined with machine learning approaches, such as neural networks and hidden Markov models, have made it possible to achieve a level of reliability where practical use in, for example ...
H, Nielsen, S, Brunak, G, von Heijne
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"In vitro" reconstitution of "trans"-Golgi exit and the effect of GAG attachment on protein sorting [PDF]
, 2007 The trans-Golgi network is one of the main sorting stations for proteins and lipids in the eukaryotic endomembrane system. Yet, the mechanisms for sorting and transport out of the trans-Golgi network remain poorly understood.
Kobialka, Szymon
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A cytosolic factor mediating membrane recruitment of AP-1 clathrin adaptors [PDF]
, 2008 Transport of cargo within the endocytic and secretory pathway is generally mediated by coated vesicles. These vesicles are formed through the recruitment of cytosolic coat proteins to the donor membrane that act as a scaffold to form coated buds and ...
Suri, Gregor
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, 2023 In this project we focus on the interplay between volume of sales and number of reviews and explore what happens when these signals are perceived as congruent versus ...
Signals of Popularity
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Extensive feature detection of N-terminal protein sorting signals [PDF]
Bioinformatics, 2002 Abstract Motivation: The prediction of localization sites of various proteins is an important and challenging problem in the field of molecular biology. TargetP, by Emanuelsson et al. (J. Mol. Biol. , 300, 1005–1016, 2000) is a neural network based system which is currently the best predictor in the literature for N-terminalsorting ...
Hideo Bannai +4 more
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Recruitment of AP-1 clathrin adaptors to liposomal membranes [PDF]
, 2004 Protein and membrane traffic between organelles within the endocytic and exocytic pathway is mediated most prominently by coated vesicles. These vesicles are formed by the assembly of cytosolic coat proteins onto the donor membrane, which deform it into ...
Meyer, Daniel Markus
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The c-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuole [PDF]
, 2003 We have assessed the ability of the plant secretory pathway to handle the expression of complex heterologous proteins by investigating the fate of a hybrid immunoglobulin A/G in tobacco cells.
Santoro, Aniello +6 more
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Protein A Is Released into the Staphylococcus aureus Culture Supernatant with an Unprocessed Sorting Signal [PDF]
Infection and Immunity, 2015 ABSTRACT The immunoglobulin binding protein A (SpA) of Staphylococcus aureus is synthesized as a precursor with a C-terminal sorting signal. The sortase A enzyme mediates covalent attachment to peptidoglycan so that SpA is displayed on the surface of the bacterium.
Geoghegan, Joan +2 more
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