Results 131 to 140 of about 19,302,461 (314)

The I-TASSER Suite: protein structure and function prediction

Nature Methods, 2014
Jianyi Yang, Renxiang Yan, Ambrish Roy, Dong Xu, Jonathan Poisson, Yang Zhang   +5 more
semanticscholar   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Apolipoprotein A-IV fibrils: structural diagnosis of mixed cardiac amyloidosis

Nature Communications
Cardiac amyloidosis (CA) occurs when misfolded proteins deposit as fibrils in the extracellular space of the heart. The fibrillogenic properties of apolipoprotein A-IV (ApoAIV) have been histologically observed and associated with CA pathogenesis.
Shintaro Aibara, Astrid Kassner, Edmond Wong, Karin Klingel, Monika Papworth, Magnus Althage, Qing-Dong Wang, Claudia Correia, Hendrik Milting, Taiana Maia de Oliveira   +9 more
doaj   +1 more source

Characterization of sensory and motor dysfunction and morphological alterations in late stages of type 2 diabetic mice

Frontiers in Endocrinology
Diabetic neuropathy is the most common complication of diabetes and lacks effective treatments. Although sensory dysfunction during the early stages of diabetes has been extensively studied in various animal models, the functional and morphological ...
Ting Tian, Ting Tian, Haofeng Li, Sensen Zhang, Maojun Yang, Maojun Yang   +5 more
doaj   +1 more source

Structure and Potential Applications of Polyamide 6/Protein Electro-spun Nano-fibrous Mats in Sorption of Metal Ions and Dyes from Industrial Effluents

, 2021
Hosam El‐Sayed, Salwa Mowafi, Marwa Abou Taleb, Claudia Vineis   +3 more
openalex   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Chemical crosslinking and mass spectrometry studies of the structure and dynamics of membrane proteins and receptors.

, 2005
William E. Haskins, Michael D. Leavell, Pamela Lane, Richard B. Jacobsen, Joo‐Hee Hong, Marites J. Ayson, Nichole Wood, Joseph S. Schoeniger, Gary Kruppa, Kenneth L. Sale, Malin M. Young, Petr Novák   +11 more
openalex   +2 more sources

FTMove: A Web Server for Detection and Analysis of Cryptic and Allosteric Binding Sites by Mapping Multiple Protein Structures

, 2022
Megan Egbert, George Jones, Matthew Collins, Dima Kozakov, Sándor Vajda   +4 more
openalex   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source