Results 171 to 180 of about 19,302,461 (314)

Structure of Haze Forming Proteins in White Wines: Vitis vinifera Thaumatin-Like Proteins

open access: gold, 2014
Matteo Marangon   +3 more
openalex   +2 more sources

Structure-Guided Optimization Provides a Series of TTK Protein Inhibitors with Potent Antitumor Activity

open access: green, 2021
Jan Elsner   +14 more
openalex   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

open access: yesFEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi   +5 more
wiley   +1 more source

Most autophagic cell death studies lack evidence of causality

open access: yesFEBS Open Bio, EarlyView.
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley   +1 more source

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

open access: yesFEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki   +3 more
wiley   +1 more source

Segmental Allergen Challenge Alters Multimeric Structure and Function of Surfactant Protein D in Humans

open access: green, 2010
Elena N. Atochina‐Vasserman   +7 more
openalex   +2 more sources

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