Results 181 to 190 of about 3,699,805 (346)

Caver Web: Detection of tunnels and channels in protein structures and analysis of ligand transport processes

, 2020
Jan Štourač, Ondřej Vávra, Piia Kokkonen, Jiří Filipovič, Gaspar Pinto, Jan Brezovský, David Bednář, Jiřı́ Damborský   +7 more
openalex   +1 more source

Salt-Bridges in the Microenvironment of Stable Protein Structures [PDF]

, 2020
Amal Kumar Bandyopadhyay
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Top-Down Scoring of Spectral Fitness by Image Analysis for Protein Structure Validation. [PDF]

J Chem Inf Model
Harding BD, DeZonia B, Garg R, Hu Z, Delaglio F, Grant T, Rienstra CM.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

AlphaFold Protein Structure Database 2025: a redesigned interface and updated structural coverage. [PDF]

Nucleic Acids Res
Bertoni D, Tsenkov M, Magana P, Nair S, Pidruchna I, Querino Lima Afonso M, Midlik A, Paramval U, Lawal D, Tanweer A, Last M, Patel R, Laydon A, Lasecki D, Dietrich N, Tomlinson H, Žídek A, Green T, Kovalevskiy O, Lau A, Kandathil S, Bordin N, Sillitoe I, Mirdita M, Jones D, Orengo C, Steinegger M, Fleming JR, Velankar S.   +28 more
europepmc   +1 more source

Rotavirus non-structural proteins: structure and function

, 2012
Liya Hu, Sue E. Crawford, Joseph M. Hyser, Mary K. Estes, B. V. Venkataram Prasad   +4 more
openalex   +2 more sources

Structures of β-Ketoacyl-Acyl Carrier Protein Synthase I Complexed with Fatty Acids Elucidate its Catalytic Machinery [PDF]

, 2001
Johan G. Olsen, Anders Kadziola, Penny von Wettstein‐Knowles, Mads Siggaard-Andersen, Sine Larsen   +4 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A knot in the protein structure – probing the near‐infrared fluorescent protein iRFP designed from a bacterial phytochrome [PDF]

, 2014
Olesya V. Stepanenko, Grigory S. Bublikov, Olga V. Stepanenko, Daria M. Shcherbakova, Vladislav V. Verkhusha, Konstantin К. Turoverov, Irina М. Kuznetsova   +6 more
openalex   +1 more source