Results 291 to 300 of about 3,840,867 (319)

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Modifications in Protein Structure and Xanthine Oxidase Inhibition of Yak Casein Induced by Protease Treatment. [PDF]

Food Sci Nutr
Shang G, Deng M, Zhang Y, Suo H, Song J.
europepmc   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Using Large Language Model to Optimize Protein Purification: Insights from Protein Structure Literature Associated with Protein Data Bank. [PDF]

Adv Sci (Weinh)
Chen Z, Sivaraman J.
europepmc   +1 more source

An end-to-end framework for the prediction of protein structure and fitness from single sequence. [PDF]

Nat Commun
Chen Y, Xu Y, Liu D, Xing Y, Gong H.
europepmc   +1 more source

The Human OCTN Sub-Family: Gene and Protein Structure, Expression, and Regulation. [PDF]

Int J Mol Sci
Galluccio M, Tripicchio M, Pochini L.
europepmc   +1 more source

AlzDiscovery: A computational tool to identify Alzheimer's disease-causing missense mutations using protein structure information. [PDF]

Protein Sci
Pan Q, Parra GB, Myung Y, Portelli S, Nguyen TB, Ascher DB.   +5 more
europepmc   +1 more source

Rational design of¹⁹F NMR labelling sites to probe protein structure and interactions

Streit JO, Chan SH, Daya S, Christodoulou J.   +3 more
europepmc   +1 more source

A Perspective on Protein Structure Prediction Using Quantum Computers. [PDF]

J Chem Theory Comput
Doga H, Raubenolt B, Cumbo F, Joshi J, DiFilippo FP, Qin J, Blankenberg D, Shehab O.   +7 more
europepmc   +1 more source

In the twilight zone of protein sequence homology: do protein language models learn protein structure? [PDF]

Bioinform Adv
Kabir A, Moldwin A, Bromberg Y, Shehu A.
europepmc   +1 more source