Results 111 to 120 of about 711,796 (313)
Alignment of the amino terminal amino acid sequence of human cytochrome c oxidase subunits I and II with the sequence of their putative mRNAs [PDF]
, 1981 Thirteen of the first fifteen amino acids from the NH2-terminus of the primary sequence of human cytochrome c oxidase subunit I and eleven of the first twelve amino acids of subunit II have been identified by microsequencing procedures.
Attardi, Giuseppe +2 more
core +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
A mathematical model of protein subunits COVID-19 vaccines. [PDF]
Math Biosci, 2023 Gholami S +7 more
europepmc +1 more source
The G Protein Subunit Gene Families
Genomics, 1999 t i t u p g s t ( uch as neurotransmitters, hormones, and light. The vast ajority of such receptors are coupled to G proteins, which ransduce the signal to effectors. G proteins are heterotrimrs made up of an a, a b, and a g subunit (29). The G protein ubunits are now known to be encoded by families of related enes in mammalian cells (74). The sizes of
G B, Downes, N, Gautam
openaire +2 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different G protein subunits. [PDF]
Mol Cell, 2023 Park JC +9 more
europepmc +1 more source
Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by Gβγ subunits and function as heteromultimers [PDF]
, 1995 Guanine nucleotide-binding proteins (G proteins) activate K+ conductances in cardiac atrial cells to slow heart rate and in neurons to decrease excitability. cDNAs encoding three isoforms of a G-protein-coupled, inwardly rectifying K+ channel (GIRK) have
Davidson, Norman +2 more
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Diversity of heterotrimeric G-protein γ subunits in plants
BMC Research Notes, 2012 Background Heterotrimeric G-proteins, consisting of three subunits Gα, Gβ and Gγ are present in most eukaryotes and mediate signaling in numerous biological processes.
Trusov Yuri +2 more
doaj +1 more source
Agonist-Dependent Coupling of the Promiscuous Adenosine A2B Receptor to Gα Protein Subunits. [PDF]
ACS Pharmacol Transl Sci, 2022 Voss JH +3 more
europepmc +1 more source