Results 251 to 260 of about 711,796 (313)

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Mitochondrial translational control in cardiovascular diseases: from mechanisms to therapies. [PDF]

Redox Biol
Deng Y, Guo N, Li D, Wang Z.
europepmc   +1 more source

NorQD AAA+ complex drives metal insertion by a twisting mechanism. [PDF]

Nat Commun
Kahle M, Appelgren S, König F, Carroni M, Ädelroth P, Wendler P.   +5 more
europepmc   +1 more source

Dominant-negative PSMB10 disrupts immunoproteasome assembly and leads to transient T lymphopenia. [PDF]

J Hum Immun
Ghosh S, Wang Y, Schultheiss C, Borkhardt A, Dafun AS, Knipp L, Marwitz S, Ehl S, Soulard C, Haddad E, Dey D, Evans G, Golwala ZM, Bennstein SB, Laws HJ, Rohlfs M, Magg T, Binder M, Kreins AY, Bousquet MP, Marcoux J, Klein C, Conn GL, Meiners S, Hauck F.   +24 more
europepmc   +1 more source

Multi-omic profiling converges on proteasome subunits PSMA7/PSMB2 as targets of the sepsis-protective agent Handelin. [PDF]

Front Immunol
Chen D, Zhang Q, Wu Y, Hu Y, Chen M.
europepmc   +1 more source

The architecture and energy transfer pathways of PSI-LHCI-LHCII in the phototrophic flagellate Euglena gracilis. [PDF]

Nat Commun
Huang G, Dong S, Li L, Zhu L, Bai J, Han X, Jiang J, Ju J, Sui SF, Qin X.   +9 more
europepmc   +1 more source

Disruption of the SAGA CORE triggers collateral degradation of KAT2A. [PDF]

Nat Commun
Batty P, Beneder H, Schätz C, Onea G, Zaczek M, Kutschat AP, Abele M, Müller S, Superti-Furga G, Winter GE, Seruggia D.   +10 more
europepmc   +1 more source

The Effect of Renal Ischemia/Reperfusion on the Renal Expression of Epithelial Sodium Channels in Rat: Possible Role of Neural Precursor Cell-Expressed Developmentally Down-Regulated Protein (Nedd4-2).

Kidney Blood Press Res
Malatiali S, Fahel R, Ali RH, Redzic Z.
europepmc   +1 more source