Results 221 to 230 of about 11,322,924 (398)

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Acute Cold Exposure Cell-Autonomously Reduces mTORC1 Signaling and Protein Synthesis Independent of AMPK. [PDF]

Cells
Sung BY, Ford EJ, Foster DJ, Fullmer KJ, Cromwell C, Viollet B, Thomson DM.   +6 more
europepmc   +1 more source

Chemical synthesis of proteins

, 1996
Lynda Draffan
openalex   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Availability of Charged tRNAs Drives Maximal Protein Synthesis at Intermediate Levels of Codon Usage Bias. [PDF]

Bull Math Biol
Hill AM, To K, Wilke CO.
europepmc   +1 more source

Synthesis of an oligonucleotide-derivatized amphipol and its use to trap and immobilize membrane proteins [PDF]

, 2014
Christel Le Bon, Eduardo Antonio Della Pia, Fabrice Giusti, Noémie Lloret, Manuela Zoonens, Karen L. Martinez, Jean‐Luc Popot   +6 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Paraisariamides: Cycloheptapeptide Toxins from Entomopathogenic Fungi (Paraisaria spp.) That Inhibit Total Protein Synthesis. [PDF]

J Nat Prod
Tehan RM, Mattos DR, Arai T, Suzuki R, Paatero AO, Tranter D, Dooley CB, Rodriguez GJ, Spatafora JW, Paavilainen VO, Oishi S, Ishmael JE, McPhail KL.   +12 more
europepmc   +1 more source

Total chemical synthesis of ester-linked ubiquitinated proteins unravels their behavior with deubiquitinases

, 2018
Hao Sun, Roman Meledin, Sachitanand M. Mali, Ashraf Brik   +3 more
openalex   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source