Results 91 to 100 of about 8,970,528 (379)

Modulation of the ISFET response by an immunological reaction [PDF]

open access: yes, 1989
A new method is presented for the detection of an immunological reaction in a membrane. Antigens (or antibodies) are taken up in a porous membrane, which covers the gate area of an ISFET. By stepwise changing of the electrolyte concentration, a transient
Bergveld, P.   +4 more
core   +2 more sources

Apolipoprotein E: far more than a lipid transport protein.

open access: yesAnnual review of genomics and human genetics (Print), 2000
First recognized as a major determinant in lipoprotein metabolism and cardiovascular disease, apolipoprotein (apo) E has emerged as an important molecule in several biological processes not directly related to its lipid transport function, including ...
R. Mahley, S. C. Rall
semanticscholar   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Single-particle imaging reveals intraflagellar transport–independent transport and accumulation of EB1 in \u3cem\u3eChlamydomonas\u3c/em\u3e flagella [PDF]

open access: yes, 2016
The microtubule (MT) plus-end tracking protein EB1 is present at the tips of cilia and flagella; end-binding protein 1 (EB1) remains at the tip during flagellar shortening and in the absence of intraflagellar transport (IFT), the predominant protein ...
Harris, J. Aaron   +4 more
core   +1 more source

Molecular dissection of TatC defines critical regions essential for protein transport and a TatB–TatC contact site

open access: yesMolecular Microbiology, 2012
The twin arginine transport (Tat) system transports folded proteins across the prokaryotic cytoplasmic membrane and the plant thylakoid membrane. TatC is the largest and most conserved component of the Tat machinery.
H. Kneuper   +8 more
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Depletion of phosphatidylcholine affects endoplasmic reticulum morphology and protein traffic at the Golgi complex

open access: yesJournal of Lipid Research, 2009
The mutant Chinese hamster ovary cell line MT58 contains a thermosensitive mutation in CTP:phosphocholine cytidylyltransferase, the regulatory enzyme in the CDP-choline pathway. As a result, MT58 cells have a 50% decrease in their phosphatidylcholine (PC)
Nicole Testerink   +4 more
doaj  

CoCl2‐induced glioma hypoxia environment enhances CD47‐SIRPα to promote tumor immune evasion

open access: yesMedComm – Oncology
Elevated levels of tumor‐associated macrophages and microglia in the immune microenvironment of malignant gliomas promote tumor growth and progression.
Xiangfei Ding   +8 more
doaj   +1 more source

The Chloroplast Twin Arginine Transport (Tat) Component, Tha4, Undergoes Conformational Changes Leading to Tat Protein Transport*

open access: yesJournal of Biological Chemistry, 2012
Background: Tha4 is the assumed cpTat protein conduit for transporting folded precursors across thylakoid membranes. Results: During assembly into active Tat translocases, the Tha4 amphipathic helix (APH) and adjacent C-tail undergo accessibility changes.
Cassie Aldridge   +3 more
semanticscholar   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

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