Results 111 to 120 of about 8,268,147 (364)

Protein transport across the cell wall of monoderm Gram‐positive bacteria

open access: yesMolecular Microbiology, 2012
In monoderm (single‐membrane) Gram‐positive bacteria, the majority of secreted proteins are first translocated across the cytoplasmic membrane into the inner wall zone.
Brian M. Forster, H. Marquis
semanticscholar   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Molecular Mimicry of SecA and Signal Recognition Particle Binding to the Bacterial Ribosome

open access: yesmBio, 2019
Bacteria execute a variety of protein transport systems for maintaining the proper composition of their different cellular compartments. The SecYEG translocon serves as primary transport channel and is engaged in transporting two different substrate ...
Lara Knüpffer   +5 more
doaj   +1 more source

Cytosolic flow induced symmetry breaking in a conceptual polarity model [PDF]

open access: yesarXiv, 2020
Important cellular processes, such as cell motility and cell division, are coordinated by cell polarity, which is determined by the non-uniform distribution of certain proteins. Such protein patterns form via an interplay of protein reactions and protein transport.
arxiv  

Protein bioelectronics: a review of what we do and do not know [PDF]

open access: yes, 2017
We review the status of protein-based molecular electronics. First we discuss fundamental concepts of electron transfer and transport in and across proteins and proposed mechanisms for these processes. We then describe the immobilization of proteins to solid-state surfaces in both nanoscale and macroscopic approaches, and highlight how different ...
arxiv   +1 more source

Intracellular Transport of the S Proteins of Coronaviruses [PDF]

open access: yes, 2006
Coronaviruses mature by a budding process at intracellular membranes. For two of the viral membrane proteins, M and E, it has been shown that they are intracellularly retained. Upon single expression, the M proteins of transmissible gastroenteritis virus (TGEV) and avian infectious bronchitis virus are localized in the cis-Golgi network or cis-Golgi ...
Christel Schwegmann-Wessels   +2 more
openaire   +3 more sources

CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures

open access: yesPLoS Comput. Biol., 2012
Tunnels and channels facilitate the transport of small molecules, ions and water solvent in a large variety of proteins. Characteristics of individual transport pathways, including their geometry, physico-chemical properties and dynamics are instrumental
E. Chovancová   +12 more
semanticscholar   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Dual or Not Dual?—Comparative Analysis of Fluorescence Microscopy-Based Approaches to Study Organelle Targeting Specificity of Nuclear-Encoded Plant Proteins

open access: yesFrontiers in Plant Science, 2018
Plant cells are unique as they carry two organelles of endosymbiotic origin, namely mitochondria and chloroplasts (plastids) which have specific but partially overlapping functions, e. g., in energy and redox metabolism.
Mayank Sharma   +2 more
doaj   +1 more source

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