Results 131 to 140 of about 1,594,666 (333)

Charge transport in bacteriorhodopsin monolayers: The contribution of conformational change to current-voltage characteristics

, 2009
When moving from native to light activated bacteriorhodopsin, modification of charge transport consisting of an increase of conductance is correlated to the protein conformational change.
Alfinito, Eleonora, Reggiani, Lino
core   +1 more source

SODIUM-DEPENDENT „TRANSPORT” REACTIONS IN THE CELL NUCLEUS AND THEIR ROLE IN PROTEIN AND NUCLEIC ACID SYNTHESIS [PDF]

, 1961
V. G. Allfrey, R. Meudt, J. W. Hopkins, A. E. Mirsky   +3 more
openalex   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Directed transport as a mechanism for protein folding in vivo

, 2009
We propose a model for protein folding in vivo based on a Brownian-ratchet mechanism in the multidimensional energy landscape space. The device is able to produce directed transport taking advantage of the assumed intrinsic asymmetric properties of the ...
Alberts B., Bhutani N., Ellis R. J., Ernesto González-Candela, Kramer G., Lapanje S., Levinthal C., van Kampen N. G., Visscher K., Víctor Romero-Rochín   +9 more
core   +1 more source

ANKS1A-Deficiency Aberrantly Increases the Entry of the Protein Transport Machinery into the Ependymal Cilia. [PDF]

Mol Cells, 2023
Lee H, Lee J, Shin M, Park S.
europepmc   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

In vitro Stimulation by Insulin of α-Amino-isobutyric Acid Transport in the Absence of Protein Synthesis [PDF]

, 1963
G. R. Fritz, E. Knobil
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Coping with stress: How bacteria fine-tune protein synthesis and protein transport. [PDF]

J Biol Chem, 2023
Njenga R, Boele J, Öztürk Y, Koch HG.
europepmc   +1 more source

Presence of Two Iron-Transport Proteins in Serum [PDF]

, 1961
M Faber, R. JORDAL
openalex   +1 more source