Results 131 to 140 of about 8,268,147 (364)

Role of the Breast Cancer Resistance Protein (BCRP/ABCG2) in Drug Transport—an Update

open access: yesAAPS Journal, 2014
The human breast cancer resistance protein (BCRP, gene symbol ABCG2) is an ATP-binding cassette (ABC) efflux transporter. It was so named because it was initially cloned from a multidrug-resistant breast cancer cell line where it was found to confer ...
Qingcheng Mao, J. Unadkat
semanticscholar   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Role of boron and its interaction with other elements in plants

open access: yesFrontiers in Plant Science
Boron (B) is an essential microelement for plants, and its deficiency can lead to impaired development and function. Around 50% of arable land in the world is acidic, and low pH in the soil solution decreases availability of several essential mineral ...
Peter Vera-Maldonado   +9 more
doaj   +1 more source

Diverse roles for the p24 family of proteins in eukaryotic cells

open access: yesBiomolecular Concepts, 2012
Members of the p24 protein family form a highly conserved family of type I transmembrane proteins that are abundant components of the early secretory pathway.
Schuiki Irmgard, Volchuk Allen
doaj   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

BMI and waist circumference cut-offs for corresponding levels of insulin sensitivity in a Middle Eastern immigrant versus a native Swedish population – the MEDIM population based study

open access: yesBMC Public Health, 2016
Background The aim of this study was to identify corresponding body mass index (BMI) and waist circumference cut-offs for equivalent levels of insulin sensitivity in a Middle Eastern immigrant population compared with native Swedes.
Louise Bennet   +3 more
doaj   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

The twin arginine protein transport pathway exports multiple virulence proteins in the plant pathogen Streptomyces scabies

open access: yesMolecular Microbiology, 2010
Streptomyces scabies is one of a group of organisms that causes the economically important disease potato scab. Analysis of the S. scabies genome sequence indicates that it is likely to secrete many proteins via the twin arginine protein transport (Tat ...
M. Joshi   +10 more
semanticscholar   +1 more source

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