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Transport of Proteins into Mitochondria
1984There is still much that is obscure concerning the transport of proteins into or through the mitochondrial membrane systems. In addition, as pointed out previously, it is unlikely that the details of the process are the same for proteins destined for different compartments of the organelle. A brief summary of the process for matrix proteins might be as
Shawn Doonan +4 more
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Nucleocytoplasmic transport of proteins
Biochemistry (Moscow), 2007In eukaryotic cells, the movement of macromolecules between the nucleus and cytoplasm occurs through the nuclear pore complex (NPC)--a large protein complex spanning the nuclear envelope. The nuclear transport of proteins is usually mediated by a family of transport receptors known as karyopherins.
Alexey V. Sorokin +2 more
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Cellular and Molecular Life Sciences, 2006
The plasma membrane of epithelial cells and hepatocytes is divided into two separate membrane compartments, the apical and the basolateral domain. This polarity is maintained by intracellular machinery that directs newly synthesized material into the correct target membrane.
Delphine Delacour, Ralf Jacob
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The plasma membrane of epithelial cells and hepatocytes is divided into two separate membrane compartments, the apical and the basolateral domain. This polarity is maintained by intracellular machinery that directs newly synthesized material into the correct target membrane.
Delphine Delacour, Ralf Jacob
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2002
Publisher Summary This chapter discusses the process of nuclear protein transport. Work on the mechanism of nuclear transport has led to a fairly detailed understanding of how proteins are targeted for import or export. This work has changed the way in which researchers need to think about potential transport mechanisms for their own protein of ...
Anita H. Corbett +2 more
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Publisher Summary This chapter discusses the process of nuclear protein transport. Work on the mechanism of nuclear transport has led to a fairly detailed understanding of how proteins are targeted for import or export. This work has changed the way in which researchers need to think about potential transport mechanisms for their own protein of ...
Anita H. Corbett +2 more
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Transport of proteins into mitochondria
2007Most mitochondrial proteins are nuclear-encoded and synthesised as preproteins on polysomes in the cytosol. They must be targeted to and translocated into mitochondria. Newly synthesised preproteins interact with cytosolic factors until their recognition by receptors on the surface of mitochondria.
Truscott, Kaye N. +2 more
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Motor proteins transporting cargos
The European Physical Journal E, 2005Processive motor proteins such as kinesin and myosin-V are enzymes that use the energy of ATP hydrolysis to travel along polar cytoskeletal filaments. One of the functions of these proteins is the transport of vesicles and protein complexes that are linked to the light chains of the motors. Modeling the light chain by a linear elastic spring, and using
Zeldovich, K. B. +2 more
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Drug transport proteins in the liver
Advanced Drug Delivery Reviews, 2003Together with drug metabolising enzymes, transmembrane transporters are important determinants of drug metabolism and drug clearance by the liver. Hepatic uptake of organic anions, cations, prostaglandins and bile salts is supported by dedicated transporter proteins in the basolateral (sinusoidal) membrane of hepatocytes: OATPs, OATs, OCTs, PGTs and ...
Faber, K.N. +2 more
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1974
The relative constancy of the internal environment of the cell is maintained by a variety of transport systems which are located within the membrane. These transport systems serve to regulate the entrance and exit of various solutes concerned with the metabolic activity of the cell.
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The relative constancy of the internal environment of the cell is maintained by a variety of transport systems which are located within the membrane. These transport systems serve to regulate the entrance and exit of various solutes concerned with the metabolic activity of the cell.
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ABA Transport by ABCG Transporter Proteins
2014The superfamily of ATP-binding cassette (ABC) transporters is one of the most abundant protein families in nature. These transporters are broadly conserved from prokaryotes to higher eukaryotes, and most of them transport various metabolites and signalling molecules in an ATP-dependent manner. Plant genomes in particular have large ABC families of more
Kazuo Shinozaki, Takashi Kuromori
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PROTEINS OF AXONAL TRANSPORT: INTERACTION OF RAPIDLY TRANSPORTED PROTEINS WITH LECTINS
Journal of Neurochemistry, 1979Abstract—Rapidly transported fucose‐labelled glycoproteins from the optic system of the rabbit were solubilised with the non‐ionic detergent Berol 172.The major labelled components were bound to wheat germ agglutinin or Concanavalin A coupled to Sepharose but not to other lectins or glycoproteins.
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