Results 201 to 210 of about 3,106,622 (403)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Instability of potato proteinase inhibitor I against pepsin.

, 1982
Koichi Yoda, Toshifumi KIYOHARA, Teruo Iwasaki, Mitsuyoshi Yoshikawa   +3 more
openalex   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Assessing the efficacy of Alpha₁-Proteinase inhibitor (human) augmentation therapy for Alpha₁-Antitrypsin deficiency - Related emphysema: Challenges and opportunities. [PDF]

Heliyon
Pierce LR.
europepmc   +1 more source

Proteolysis of the 85-Kilodalton Crystalline Cysteine Proteinase Inhibitor from Potato Releases Functional Cystatin Domains

, 1993
Terence A. Walsh, James A. Strickland
openalex   +2 more sources

Inhibition of the Cathepsin D-Type Proteinase of Macrophages by Pepstatin, a Specific Pepsin Inhibitor, and Other Substances [PDF]

, 1973
Martha H. McAdoo, Arthur M. Dannenberg, Cara J. Hayes, Stephen P. James, John H. Sanner   +4 more
openalex   +1 more source

Plasma levels of neutrophil elastase-Alpha1-proteinase inhibitor complexes and factor XIII (including subunits A and S) in septicemia and leucemia [PDF]

, 1983
Duswald, Karl-Heimo, Egbring, R., Fritz, Hans, Hiller, E., Jochum, Marianne, Klingemann, H. - G.   +5 more
core   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Matrix metalloproteinase-2 and tissue inhibitor of metallo-proteinase-2 in colorectal carcinoma invasion and metastasis

, 2005
Binghui Li
openalex   +1 more source

Role of leukocytes in hemostasis during orthotopic liver transplantation [PDF]

, 1993
Bechstein, W. O., Himmelreich, G., Huhn, D., Jochum, Marianne, Machleidt, W., Muser, M., Neuhaus, P., Riess, H., Roissaint, R.   +8 more
core   +1 more source