Frontiers in Plant Science, 2016 Root-knot nematodes (RKN) cause substantial yield decline in eggplant and sustainable management options to minimize crop damage due to nematodes are still limited.
Pradeep Kumar Papolu +5 more
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A KLK4 proteinase substrate capture approach to antagonize PAR1
Scientific Reports, 2021 Proteinase-activated receptor-1 (PAR1), triggered by thrombin and other serine proteinases such as tissue kallikrein-4 (KLK4), is a key driver of inflammation, tumor invasiveness and tumor metastasis.
Eitan Rabinovitch +8 more
doaj +1 more source
Бюллетень сибирской медицины, 2007 Oxygen insufficiency in newborns is associated with disturbed vascular tone, which are regulated by kallikrein-kinin (KKS) and renin-angiotensin systems (RAS).Important index of hemodynamic disturbances is the activity of kallikrein, of angiotensin ...
G. A. Soukhanova +4 more
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Isolation, cloning and structural characterisation of boophilin, a multifunctional Kunitz-type proteinase inhibitor from the cattle tick. [PDF]
PLoS ONE, 2008 Inhibitors of coagulation factors from blood-feeding animals display a wide variety of structural motifs and inhibition mechanisms. We have isolated a novel inhibitor from the cattle tick Boophilus microplus, one of the most widespread parasites of farm ...
Sandra Macedo-Ribeiro +7 more
doaj +1 more source
Differential in vitro and in vivo effect of barley cysteine and serine protease inhibitors on phytopathogenic microorganisms [PDF]
, 2011 Protease inhibitors from plants have been involved in defence mechanisms against pests and pathogens. Phytocystatins and trypsin/α-amylase inhibitors are two of the best characterized protease inhibitor families in plants.
Cambra Marin, Ines +5 more
core +2 more sources
Activation of Proteinase 3 Contributes to Nonalcoholic Fatty Liver Disease and Insulin Resistance
Molecular Medicine, 2016 Activation of inflammatory pathways is known to accompany development of obesity-induced nonalcoholic fatty liver disease (NAFLD), insulin resistance and type 2 diabetes.
Erik J M Toonen +12 more
doaj +1 more source
Developments in plant breeding for improved nutritional quality of soya beans II. Anti-nutritional factors [PDF]
, 2000 Nutritional value of most plant materials is limited by the presence of numerous naturally occurring compounds which interfere with nutrient digestion and absorption.
Clarke, E, Wiseman, J
core +1 more source
Screening and Purification of a Chymotrypsin Inhibitor from Entrolobium Saman Seeds
Sultan Qaboos University Journal for Science, 2010 A chymotrypsin inhibitor was isolated and purified from the seeds of Enterolobium saman (Leguminaceae family) by extraction with 100 mM phosphate buffer, heat treatment, ammonium sulphate precipitation, ion-exchange chromatography on DEAEcellulose and ...
Maher Ali. Maqtari, A.B. Mohamed. Saad
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The role of the proteinase inhibitor ovorubin in apple snail eggs resembles plant embryo defense against predation. [PDF]
PLoS ONE, 2010 BACKGROUND: Fieldwork has thoroughly established that most eggs are intensely predated. Among the few exceptions are the aerial egg clutches from the aquatic snail Pomacea canaliculata which have virtually no predators. Its defenses are advertised by the
Marcos Sebastián Dreon +2 more
doaj +1 more source